Tel.
: 0431/880-2017 (Kiel) 0221/ 478-7430 (Köln) Fax
: 022/ 478 6383 Mail
: h.hansen@uni-koeln.de
LFI, Ebene 4, Raum 703 Joseph-Stelzmann-Str. 9 D-50924 KÖLN
Tel.
: 0431/880-2017 (Kiel) 0221/ 478-7430 (Köln) Fax
: 022/ 478 6383 Mail
: h.hansen@uni-koeln.de
LFI, Ebene 4, Raum 703 Joseph-Stelzmann-Str. 9 D-50924 KÖLN
|
Selected Publications
|
| 54 | Valinia S, Hansen HP, Futter MN, Bishop K, Sriskandarajah N, Fölster J. Problems with the reconciliation of good ecological status and public participation in the Water Framework Directive. Sci Total Environ. 2012 Jul 20;433C:482-490. |
| 53 | Simhadri VL, Hansen HP, Simhadri VR, Reiners KS, Bessler M, Engert A, von Strandmann EP. A novel role for reciprocal CD30-CD30L signaling in the cross-talk between natural killer and dendritic cells. Biol Chem. 2012 Jan 1;393(1-2):101-6. |
| 52 | Hansen HP, Lee A, van Randwijk CB. Patient aspects: a review of fifty-eight Danish HTA reports. Int J Technol Assess Health Care. 2011 Oct;27(4):330-6. |
| 51 | Tjørnhøj-Thomsen T, Hansen HP. Knowledge in health technology assessment: who, what, how? Int J Technol Assess Health Care. 2011 Oct;27(4):324-9. |
| 50 | Facey KM, Hansen HP. Patient-focused HTAs. Int J Technol Assess Health Care 2011 Oct;27(4):273-4. |
| 49 | Hansen HP, Draborg E, Kristensen FB. Exploring qualitative research synthesis: the role of patients’ perspectives in health policy design and decision making. Patient. 2011;4(3):143-52. |
| 48 | La Cour K, Hansen HP. Aesthetic engagements: "being" in everyday life with advanced cancer. Am J Hosp Palliat Care. 2012 Mar;29(2):126-33. |
| 47 | Hansen DG, Søndergaard J, Hansen HP, Johansen C. Adult cancer rehabilitation. Ugeskr Laeger. 2011 Jun 13;173(24):1725-7. Danish. |
| 46 | Jachimowicz RD, Fracasso G, Yazaki PJ, Power BE, Borchmann P, Engert A, Hansen HP, Reiners KS, Marie M, von Strandmann EP, Rothe A. Induction of in vitro and in vivo NK cell cytotoxicity using high-avidity immunoligands targeting prostate-specific membrane antigen in prostate carcinoma. Mol Cancer Ther. 2011 Jun;10(6):1036-45. |
| 45 | Henriksen N, Tjørnhøj-Thomsen T, Hansen HP. Illness, everyday life and narrative montage: the visual aesthetics of cancer in Sara Bro’s Diary. Health (London). 2011 May;15(3):277-97. |
| 44 | Hansen HP, Tjørnhøj-Thomsen T, Johansen C. Rehabilitation interventions for cancer survivors: The influence of context. Acta Oncol. 2011 Feb;50(2):259-64. |
| 43 | Nielsen SE, Hansen HP, Jensen BR, Parving HH, Rossing P. Urinary neutrophil gelatinase-associated lipocalin and progression of diabetic nephropathy in type 1 diabetic patients in a four-year follow-up study. Nephron Clin Pract. 2011;118(2):c130-5. |
| 42 | Hübel K, Cremer B, Heuser E, von Strandmann EP, Hallek M, Hansen HP. A prospective study of serum soluble CD30 in allogeneic hematopoietic stem cell transplantation. Transpl Immunol. 2010 Aug;23(4):215-9. |
| 41 | Rasmussen DM, Hansen HP, Elverdam B. How cancer survivors experience their changed body encountering others. Eur J Oncol Nurs. 2010 Apr;14(2):154-9. |
| 40 | Vahdat AM, Reiners KS, Simhadri VL, Eichenauer DA, Böll B, Chalaris A, Simhadri VR, Wiegmann K, Krell HW, Rose-John S, Engert A, von Strandmann EP, Hansen HP. TNF-alpha-converting enzyme (TACE/ADAM17)-dependent loss of CD30 induced by proteasome inhibition through reactive oxygen species. Leukemia. 2010 Jan;24(1):51-7. |
| 39 | Lee A, Skött LS, Hansen HP. Organizational and patient-related assessments in HTAs: state of the art. Int J Technol Assess Health Care. 2009 Oct;25(4):530-6. |
| 38 | Böll B, Eltaib F, Reiners KS, von Tresckow B, Tawadros S, Simhadri VR, Burrows FJ, Lundgren K, Hansen HP, Engert A, von Strandmann EP. Heat shock protein 90 inhibitor BIIB021 (CNF2024) depletes NF-kappaB and sensitizes Hodgkin's lymphoma cells for natural killer cell-mediated cytotoxicity. Clin Cancer Res. 2009 Aug 15;15(16):5108-16. |
| 37 | Hansen HP, Tjørnhøj-Thomsen T. Cancer rehabilitation in Denmark: the growth of a new narrative. Med Anthropol Q. 2008 Dec;22(4):360-80. |
| 36 | Henriksen N, Hansen HP. Marked bodies and selves: a literary-semiotic perspective on breast cancer and identity. Commun Med. 2009;6(2):143-52. |
| 35 | Simhadri VR, Reiners KS, Hansen HP, Topolar D, Simhadri VL, Nohroudi K, Kufer TA, Engert A, Pogge von Strandmann E. Dendritic cells release HLA-B-associated transcript-3 positive exosomes to regulate natural killer function. PLoS One. 2008;3(10):e3377. |
| 34 | Schjoedt KJ, Hansen HP, Tarnow L, Rossing P, Parving HH. Long-term prevention of diabetic nephropathy: an audit. Diabetologia 2008 Jun;51(6):956-61. |
| 33 | Holt J, Hansen HP, Jarløv JO. Hand hygiene—is it really that difficult? Ugeskr Laeger. 2007 Nov 26;169(48):4167-9. Danish. |
| 32 | Pogge von Strandmann E, Simhadri VR, von Tresckow B, Sasse S, Reiners KS, Hansen HP, Rothe A, Böll B, Simhadri VL, Borchmann P, McKinnon PJ, Hallek M, Engert A. Human leukocyte antigen-B-associated transcript 3 is released from tumor cells and engages the NKp30 receptor on natural killer cells. Immunity 2007 Dec;27(6):965-74. |
| 31 | von Tresckow B, von Strandmann EP, Sasse S, Tawadros S, Engert A, Hansen HP. Simvastatin-dependent apoptosis in Hodgkin's lymphoma cells and growth impairment of human Hodgkin’s tumors in vivo. Haematologica 2007 May;92(5):682-5. |
| 30 | Eichenauer DA, Simhadri VL, von Strandmann EP, Ludwig A, Matthews V, Reiners KS, von Tresckow B, Saftig P, Rose-John S, Engert A, Hansen HP. ADAM10 inhibition of human CD30 shedding increases specificity of targeted immunotherapy in vitro. Cancer Res. 2007 Jan 1;67(1):332-8. |
| 29 | von Strandmann EP, Hansen HP, Reiners KS, Schnell R, Borchmann P, Merkert S, Simhadri VR, Draube A, Reiser M, Purr I, Hallek M, Engert A. A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural killer (NK) cells and CD138 activates NK cells and has potent antitumor activity against human multiple myeloma in vitro and in vivo. Blood. 2006 Mar 1;107(5):1955-62. |
| 28 | Matthey B, Borchmann P, Schnell R, Tawadros S, Lange H, Huhn M, Klimka A, Tur MK, Barth S, Engert A, Hansen HP. Metalloproteinase inhibition augments antitumor efficacy of the anti-CD30 immunotoxin Ki-3(scFv)-ETA' against human lymphomas in vivo. Int J Cancer. 2004 Sep 10;111(4):568-74. |
| 27 | Reiners KS, Hansen HP, Krüssmann A, Schön G, Csernok E, Gross WL, Engert A, von Strandmann EP. Selective killing of B-cell hybridomas targeting proteinase 3, Wegener’s autoantigen. Immunology. 2004 Jun;112(2):228-36. |
| 26 | von Tresckow B, Kallen KJ, von Strandmann EP, Borchmann P, Lange H, Engert A, Hansen HP. Depletion of cellular cholesterol and lipid rafts increases shedding of CD30. J Immunol. 2004 Apr 1;172(7):4324-31. |
| 25 | Hansen HP, Recke A, Reineke U, Von Tresckow B, Borchmann P, Von Strandmann EP, Lange H, Lemke H, Engert A. The ectodomain shedding of CD30 is specifically regulated by peptide motifs in its cysteine-rich domains 2 and 5. FASEB J. 2004 May;18(7):893-5. |
| 24 | Rossing K, Christensen PK, Andersen S, Hovind P, Hansen HP, Parving HH; Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria Study. Comparative effects of Irbesartan on ambulatory and office blood pressure: a substudy of ambulatory blood pressure from the Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria study. Diabetes Care. 2003 Mar;26(3):569-74. |
| 23 | Gaede P, Hansen HP, Parving HH, Pedersen O. Impact of low-dose acetylsalicylic acid on kidney function in type 2 diabetic patients with elevated urinary albumin excretion rate. Nephrol Dial Transplant. 2003 Mar;18(3):539-42. |
| 22 | Dong L, Hülsmeyer M, Dürkop H,
Hansen HP, Schneider-Mergener J, Ziegler A, Uchanska-Ziegler B. |
| 21 | Schnell R, Staak O, Borchmann P, Schwartz
C, Matthey B, Hansen HP, Schindler J, Ghetie V, Vitetta ES, Diehl
V, Engert A. A Phase I study with an anti-CD30 ricin A-chain immunotoxin (Ki-4.dgA) in patients with refractory CD30+ Hodgkin's and non-Hodgkin's lymphoma. Clin Cancer Res. 2002;8:1779-1786. |
| 20 | Maehnss K, Kobarg J, Schmitt WH, Hansen
HP, Lange H, Csernok E, Gross WL, Lemke H. Vitronectin- and Fibronectin-containing Immune Complexes in Primary Systemic Vasculitis. J Autoimmun. 2002;18:239-250. |
| 19 | Hansen HP, Matthey B, Barth S, Kisseleva
T, Mokros T, Davies SJ, Beckett RP, Foelster-Holst R, Lange HH, Engert A,
Lemke H. Inhibition of metalloproteinases enhances the internalization of anti- CD30 antibody Ki-3 and the cytotoxic activity of Ki-3 immunotoxin. Int J Cancer. 2002;98:210-215. |
| 18 | Folster-Holst R, Henseler T, Wehde J, Lemke
H, Weichenthal M, Christophers E, Hansen HP. Soluble CD30 plasma concentrations correlate with disease activity in patients with atopic dermatitis. Acta Derm Venereol. 2002;82:245-248 |
| 17 | Lamprecht P, Moosig F, Gause A, Herlyn K,
Csernok E, Hansen HP, Gross WL. Immunological and clinical follow up of hepatitis C virus associated cryoglobulinaemic vasculitis. Ann Rheum Dis. 2001;60:385-390. |
| 16 | Schonermarck U, Csernok E, Trabandt A, Hansen
H, Gross WL. Circulating cytokines and soluble CD23, CD26 and CD30 in ANCA- associated vasculitides. Clin Exp Rheumatol. 2000;18:457-463. |
| 15 | Hansen HP, Dietrich S, Kisseleva
T, Mokros T, Mentlein R, Lange HH, Murphy G, Lemke H. CD30 shedding from Karpas 299 lymphoma cells is mediated by TNF-alpha- converting enzyme. J Immunol. 2000;165:6703-6709. |
| 14 | Lange H, Kobarg J, Yazynin S, Solterbeck
M, Henningsen M, Hansen H, Lemke H. Genetic analysis of the maternally induced affinity enhancement in the non-Ox1 idiotypic antibody repertoire of the primary immune response to 2-phenyloxazolone. Scand J Immunol. 1999;49:55-66. |
| 13 | Klimka A, Barth S, Matthey B, Roovers RC,
Lemke H, Hansen H, Arends JW, Diehl V, Hoogenboom HR, Engert A. An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETA') is a potent immunotoxin against a Hodgkin-derived cell line. Br J Cancer. 1999;80:1214-1222 |
| 12 | Seeger M, Thierse HJ, Lange H, Shaw L, Hansen
H, Lemke H. Antigen-independent suppression of the IgE immune response to bee venom phospholipase A2 by maternally derived monoclonal IgG antibodies. Eur J Immunol. 1998;28:2124-2130. |
| 11 | Wang G, Hansen H, Tatsis E, Csernok
E, Lemke H, Gross WL. High plasma levels of the soluble form of CD30 activation molecule reflect disease activity in patients with Wegener's granulomatosis. Am J Med. 1997;102:517-523 |
| 10 | Kobarg J, Schnittger S, Fonatsch C, Lemke
H, Bowen MA, Buck F, Hansen HP. Characterization, mapping and partial cDNA sequence of the 57-kD intracellular Ki-1 antigen. Exp Clin Immunogenet. 1997;14:273-280 |
| 9 | Wang X, Havsteen B, Hansen H. Evidence of the coevolution of a snake toxin and its endogenous antitoxin cloning, sequence and expression of a serum albumin cDNA of the Chinese cobra. Biol Chem Hoppe Seyler. 1995;376:545-553. |
| 8 | Horn-Lohrens O, Tiemann M, Lange H, Kobarg
J, Hafner M, Hansen H, Sterry W, Parwaresch RM, Lemke H. Shedding of the soluble form of CD30 from the Hodgkin-analogous cell line L540 is strongly inhibited by a new CD30-specific antibody (Ki-4). Int J Cancer. 1995;60:539-544 |
| 7 | Hansen HP, Kisseleva T, Kobarg J,
Horn-Lohrens O, Havsteen B, Lemke H. A zinc metalloproteinase is responsible for the release of CD30 on human tumor cell lines. Int J Cancer. 1995;63:750-756. |
| 6 | Hansen H, Lemke H, Bodner U. Rapid and simple purification of PCR products by direct band elution during agarose gel electrophoresis. Biotechniques. 1993;14:28-30. |
| 5 | Rohde D, Hansen H, Hafner M, Lange
H, Mielke V, Hansmann ML, Lemke H. Cellular localizations and processing of the two molecular forms of the Hodgkin-associated Ki-1 (CD30) antigen. The protein kinase Ki-1/57 occurs in the nucleus. Am J Pathol. 1992;140:473-482 |
| 4 | Hansen H, Bredfeldt G, Havsteen B,
Lemke H. Protein kinase activity of the intracellular but not of the membrane-associated form of the Ki-1 antigen (CD30). Res Immunol. 1990;141:13-31 |
| 3 | Lemke H, Huss G, Bonmann J, Hansen H.
Determination of cell-bound Fc receptors using a cell adherence test (CAT). J Immunol Methods. 1989;121:175-183. |
| 2 | Hansen H, Lemke H, Bredfeldt G, Konnecke
I, Havsteen B. The Hodgkin-associated Ki-1 antigen exists in an intracellular and a membrane-bound form. Biol Chem Hoppe Seyler. 1989;370:409-416 |
| 1 | Froese P, Lemke H, Gerdes J, Havsteen B,
Schwarting R, Hansen H, Stein H. Biochemical characterization and biosynthesis of the Ki-1 antigen in Hodgkin-derived and virus-transformed human B and T lymphoid cell lines. J Immunol. 1987;139:2081-2087. |
|
Research
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|
1. Regulation of metalloproteinase-dependent receptor
shedding |