IRTG Concept Program Organization Members Downloads Publications Contact


Within the framework of the Collaborative Research Center (CRC) 877 „Proteolysis as a Regulatory Event in Pathophysiology“ an „Integrated Research Training Group: Proteases and Pathophysiology“ has been established and offers:

Doktorhut10 MD stipends per year

Prerequisite is the participation in the research of one of the scientific projects of the CRC 877. The general aim of the CRC 877 is to obtain a profound understanding of proteolytic processes in cellular regulation and signaling and to define the involvement of such processes in human pathophysiology. For example, the Tumor Necrosis Factor (TNF) needs to be cleaved in order to act systemically; we believe that this proteolytic cleavage is a key step in the development of inflammatory diseases. The goal of the CRC 877 is to define the molecular mechanisms regulating the proteolytic steps in signaling cascades and to understand the conceptional difference between proteolytic steps and other fast and reversible signaling events such as phosphorylation and methylation. This understanding will not only help to define pathophysiologic situations mediated by cytokines and growth factors but also to define points of intervention for the development of novel therapeutic principles.

Contact: Prof. Dr. Christoph Becker-Pauly, Biochemisches Institut an der CAU Kiel, Otto-Hahn-Platz 9, 24118 Kiel
Phone: +49-431-880-7118

Aushang IRTG 2018 Flyer IRTG 2018 Poster der IRTG zur Kieler Woche
Forum UKSH 04/2011 Titelseite Article in Forum UKSH 04/2011
An article about two IRTG students in the magazine "UKSH Forum", issue April 2011

Template by OS Templates