Collaborative Research Centre 877

Proteolysis as a Regulatory Event in Pathophysiology

Christian-Albrechts-Universität zu Kiel

Education and Academic Positions
1998 Habilitation in Immunology, University of Kiel
1988–1990 Dissertation at the Max-Planck-Institute for Biochemistry, Martinsried
1982–1987 Studies of Biology, Ludwig-Maximilians-University, Munich
Research Experience
Since 2003 E14 Professor at the Institute of Immunology, University of Kiel
Since 1995 Principal Investigator at the Institute of Immunology, University of Kiel
1993-1995 Post-Doc at the Institute for Medical Microbiology and Hygiene, Technical University of Munich
1991–1993 Post-Doc at the Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey, USA
1991 Post-Doc at the Max-Planck-Institute for Biochemistry, Martinsried
List of 4 Selected Publications
1. Sosna J, Voigt S, Mathieu S, Lange A, Thon L, Davarnia P, Herdegen T, Linkermann A, Rittger A, Chan FK, Kabelitz D, Schütze S, Adam D (2014) TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death. Cell Mol Life Sci 71: 331-348
2. Thon L, Möhlig H, Mathieu S, Lange A, Bulanova E, Winoto-Morbach S, Schütze S, Bulfone-Paus S, Adam D (2005) Ceramide mediates caspase-independent programmed cell death. FASEB J 19: 1945-1956
3. Strelow A, Bernardo K, Adam-Klages S, Linke T, Sandhoff K, Krönke M, Adam D (2000) Overexpression of acid ceramidase protects from tumor necrosis factor-induced cell death. J Exp Med 192: 601-611
4. Adam D, Dimitrijevic N, Schartl M (1993) Tumor suppression in Xiphophorus by an accidentally acquired promoter. Science 259: 816-819