Collaborative Research Centre 877

Proteolysis as a Regulatory Event in Pathophysiology

Christian-Albrechts-Universität zu Kiel

Seminars & Invited Speakers

2019 - Invited Speakers for the CRC Seminars (usually on Tuedays unless otherwise indicated)
Download the list of seminars as of October 2019 (PDF)
Date Speaker Topic
28 April 2020 Nigel Emtage, University of Oxford, Medical Sciences Division (to be announced)
17 Dec 2019 Prof. Dr. Philip Wenzel, Kardiologie I; Johannes-Gutenberg-Universität Mainz Thromboinflammation in Vascular Dysfunction and Heart Disease - Role for Proteases
3 Dec 2019 Prof. Arturo Zychlinsky, PhD, Max Planck Institute for Infection Biology, Berlin NETs – the Second Function of Chromatin
29 Oct 2019 Prof. Dr. Mohamed I. Saad, Hudson Institute of Medical Research, Clayton, Melbourne, Victoria, Australia The role of the protease ADAM17 in lung carcinogenesis: Pathophysiology and translational perspectives
22 Oct 2019 Prof. Dr. Christian Klämbt, Institut für Neuro- und Verhaltensbiologie, Universität Münster Divide and Conquer: how glia separates and unites neurons in the fly brain
7 May 2019 Steven Blacklow, MD–PhD, Havard Medical School, Boston, USA Molecular Mechanisms of Notch Signal Transduction in Normal and Pathophysiologic States
2 Apr 2019 Colin Adrian, PhD, Instituto Gulbenkain de Ciéncia, Qeiras, Portugal Physiological and molecular roles of iRhom proteins in inflammation and metabolism
19 Mar 2019 Joseph F. Arboleda-Velasquez, MD, PhD, Havard Medical School, Boston, USA Notch signaling in small vessel stability and cerebrovascular disease
(Seminar will take place at the UKE in Hamburg)
16 Jan 2019
Wednesday
Prof. Dr. Dr. Christian Haass, LMU München Function and Dysfunction of microglia cells in neurodegenerative disorders
 
2019 - Invited Speakers for the IRTG Seminars "Science Meets Industry"
Date Speaker Topic
8 April 2019
Monday 15:30
PD Dr. Malte Peters, Chief Development Officer, Morphosys AG Modern Drug Development in a Biotechnology Company: getting an anti-CD19 antibody approved in Lymphoma
 
2018 - Invited Speakers for the CRC Seminars
Date Speaker Topic
4 Dec 2018 Prof. Dr. Sascha Weggen, Universität Düsseldorf A secreted metalloprotease implicates oligodendrocytes in the pathogenesis of Alzheimer's disease
 
2017 - Invited Speakers for the CRC Seminars
Date Speaker Topic
21 Nov 2017 Prof. Dr. Gunnar Hansson, Medical Biochemistry, University of Gothenburg, Sweden Proteolytic processing of the intestinal MUC2 mucin and im­portance for first and second defense lines protecting from colitis.
27 Oct 2017 Prof. Dr. Alexander Scheffold, Charité – Universitätsmedizin Berlin, Rheumatologie und Klinische Im­mu­no­lo­gie Notch-mediated regulation of anti-inflammatory CD4 T cell responses.
23 May 2017 Prof. Dr. Stefan Linder, UKE Hamburg, Institut für me­di­zi­ni­sche Mikrobiologie, Virologie und Hygiene Novel regulators and functions ofmetalloproteinase MT1-MMP in primary macrophages.
16 May 2017 Prof. Dr. Erwin F. Wagner, Centro Nacional de In­ves­ti­ga­cio­nes Oncológicas (cnio) Madrid, Spain Stress signalling by AP-1 (Fos/Jun) in inflammation and cancer.
11 Apr 2017 Dr. Marc-Phillip Hitz, Kardiologie, Uni­ver­si­täts­klinikum Schles­wig-Holstein Genetic architecture of congenital heart defects and functional follow-up of a newly identified metalloprotease.
14 Mar 2017 Prof. Dr. Philipp Lang, Molekulare Medizin II, Universitätsklini­kum Düsseldorf Immune functions during infections and tissue damage.
21 Feb 2017 Prof. Dr. Admar Verschoor, Institut für Systemische Ent­zün­dungs­for­schung, Universität Lübeck Complement, antigen handling and adaptive immunity.
24 Jan 2017 Dr. Marina Mikhaylova, ZMNH, Universitätsklinikum Hamburg-Ep­pendorf Novel insights on the structural and function properties of F-actin in dendritic spines.
 
2017 - Invited Speakers for the IRTG Seminars "Science Meets Industry"
Date Speaker Topic
5 May 2017 Dr. Helge Schmidt, Sales Manager Photonics D/A/CH bei Hübner GmbH & Co. KG (ehemals Olympus Deutschland GmbH) Science and Sales! Personal experiences within different companies, structures and hierarchies
31 Mar 2017 Dr. Susann Voigt, Project Quality Lead II, Medical Imaging, PAREXEL International GmbH, Berlin
Dr. Benjamin Schönbeck, EMEA Product Manager Haematology, Sysmex Europe GmbH, Norderstedt

Former IRTG students talk about their present jobs
20 Jan 2017 Sabine Bartels, Gebietsmangerin im Vertrieb
Dr. Christoph Kröger, Sales Manager Nord im Vertrieb; Regionalleiter
Two Sales Managers from Eppendorf AG will present their professional career & their work
Eppendorf Vertrieb Deutschland GmbH, Wesseling-Berzdorf (in cooperation with GRK 1459)
 
2016 - Invited Speakers for the CRC Seminars
Date Speaker Topic
20 Dec 2016 Dr. Boris Strilic, Max Planck Institute for Heart and Lung Research, Dep. Pharmacology, Bad Nauheim Tumour-cell-induced endothelial cell necroptosis promotes metastasis.
12 Jul 2016 PD Dr. Lars Redecke, Biochemie, Universität Lübeck Insect Cells and Free-Electron Lasers - Novel Strategies for Structural Biology.
28 Jun 2016 Dr. Guido Hansen, Biochemie, Universität Lübeck Regulation of proteolytic activity in intracellular pathogens.
24 May 2016 Prof. Dr. Dieter Langosch, Chemie der Biopolymere, TU München Intramembrane proteolysis – structure and dynamics of enzymes and substrates.
16 Feb 2016 Prof. Dr. Karl Kunzelmann, Institut für Physiology, Universität Regensburg Intracellular Ca2+ signaling: a common link to diverse functions of Anoctamins.
12 Jan 2016 Dr. Azaaq Belaaouaj, CHU de Reims, France Neutrophil elastase: Pathogen killer or pathogenic?
 
2015 - Invited Speakers for the CRC Seminars
Date Speaker Topic
15 Nov 2015 Dr. Ana-Maria Lennon-Duménil, Immunité et Cancer INSERM, Paris, France Coordination of cell migration and cell function: lessons from dendritic cells.
22 Sep 2015 Prof. Dr. Lawrence Rajendran, Neuroscience Center, Zürich, Switzerland Specific Inhibition of secretases involved in Alzheimer’s disease for therapy.
9 Jun 2015 Prof. Dr. Thomas Reinheckel, Molecular Medicine and Cell Research, Freiburg Genetic analysis of lysosomal proteases in mouse models of human cancers.
3 Mar 2015 Prof. Dr. Irit Sagi, Weizmann Institute of Science, Rehovot, Israel ECM remodeling: bystanders or partners on a crime?
27 Jan 2015 Dr. Grazyna Kwapiszewska, Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria Meprins in Lung Diseases.
 
2015 - Invited Speakers for the IRTG Seminars "Science Meets Industry"
Date Speaker Topic
6 Mar 2015 Joachim Müller-Jung, FAZ Natur und Wissenschaft/Feuilleton Wissenschaftsjournalismus
3 Feb 2015 Prof. Dr. Patrick Baeuerle, AMGEN Research (Munich) GmbH T Cell-engaging Antibody Constructs for Cancer Therapy
3 Feb 2015 Dr. Birgit Oppmann, Leibniz-Institut für Molekulare Pharmakologie, Berlin Towards Implementation of Basic Research - Technology Transfer at the Leibniz-Institut für Molekulare Pharmakologie
 
2014 - Invited Speakers for the CRC Seminars
Date Speaker Topic
2 Dec 2014 PD Dr. Dieter E. Jenne, MPI Neurobiologie, Martinsried Serine proteases of immune cells: intensifiers of defense and destruction.
4 Nov 2014 Dr. Michaela Schweizer, Zentrum für Molekulare Neurobiologie, Hamburg Immunohistochemistry in light- and electron microscopy.
26 Aug 2014 Matthias Voss, Adolf-Butenandt-Institute for Biochemistry, LMU Munich Signal peptide peptidase-like 3 affects cellular N-glycosylation by facilitating proteolytic secretion of glycosyltransferases.
8 Jul 2014 Prof. Dr. Klaus Pietrzik, Universität Mainz A Potential Role of Meprin beta in Sporadic Alzheimer’s Disease Development.
1 Jul 2014 Prof. Dr. Ulrich auf dem Keller, ETH Zürich Protease Degradomics - Dissecting Proteolysis in Skin Inflammation and Repair.
 
2013 - Invited Speakers for the CRC Seminars
Date Speaker Topic
19 Nov 2013 Prof. Dr. Chiara Zuccato, Department of BioSciences and Center for Stem Cell Research, Università degli Studi di Milano, Italy An evolutionary recent function of Huntington in development reveals a new enzymatic pathway affected in Huntington’s Disease.
22 Oct 2013 Prof. Dr. Andreas Herrlich, Harvard Medical School, Boston, USA Inside-out regulation of ectodomain protease accessibility.
25 Jun 2013 Prof. Dr. Reinhard Fässler, Max Planck Institute of Biochemistry, Molecular Medicine, Martinsried How integrin integrity is controlled in endosomes.
4 Jun 2013 Prof. Dr. Jan Münch, Institute of Molecular Virology, Ulm University Medical Center Identification and characterization of an albumin fragment as endogenous antagonist of CXCR4.
7 May 2013 Prof. Dr. Claude Libert, Mouse Genetics in Inflammation (MGI), DMBR, VIB, UGent, Belgium New roles of a selected group of MMPs in endotoxemia and sepsis.
26 Feb 2013 Prof. Dr. Ulrike Müller, Department of Pharmacy and Molecular Biotechnology, University Heidelberg Functions of the ADAM substrate APP for dendritic morphology and brain physiology.
 
2013 - Invited Speakers in the course of the Visiting Researchers Programme
Date Speaker Topic
16 Apr 2013 Prof. Dr. Ann Ager, Institute of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK ADAMs and ectododomain proteolytic shedding in leucocyte migrationFocus on L-selectin and ADAM17.
 
2013 - Invited Speakers for the IRTG Seminars Science Meets Industry
Date Speaker Topic
5 Jul 2013 Dr. Jürgen Henninger, Qualitätssicherung, Qualitätsmanagement und Regulatory Affairs Als Sisyphos zum Garant von Qualität.
21 Jun 2013 Dr. Jenny Schröder, R&D Scientist, Lonza Pharma – Bioscience Solutions, Lonza Cologne GmbH, Köln Being a Scientist at Lonza Pharma & Biotech – Bioscience Solutions.
25 Jan 2013 Dr. Barbara Krebs-Pohl, Vice President, Head of Business Development, MorphoSys AG From the white to the black side or from bench to business.
 
2012 - Invited Speakers for the CRC Seminars
Date Speaker Topic
07 Aug 2012 Michael Willem BACE1: the first cut ist the deepest.
19 Jun 2012 Daniel Teupser Genetic Factors of Atherosclerosis.
15 May 2012 Olivier Gires EpCAM signaling in health and disease.
7 Feb 2012 Dr. Jörg W. Bartsch To cleave or not to cleave: diverse roles of ADAM8 in pathology.
17 Jan 2012 Alexander Steinle Vis-à-vis in the NKC: genetically linked NK cell receptor/ligand pairs in the natural killer gene complex (NKC).
 
2012 - Invited Speakers for the IRTG Seminars Science Meets Industry
Date Speaker Topic
30 Nov 2012 Stefanie Wach The Jump of a Molecular Biologist into the World of Marketing and Global Product Management.
20 Apr 2012 Karl-Josef Kallen Science in Biotech: Challenges of Everyday Life in a Biotech Company.
 
2011 - Invited Speakers for the CRC Seminars
Date Speaker Topic
20 Dec 2011 Eric Rubensein Regulation of ADAM10 activity by tetraspanins.
20 Nov 2011 F. Xavier Gomis-Rüth Evolutionary aspects unveiled by the three-dimensional structure of metallopeptidases and their inhibitors.
8 Nov 2011 Christoph Becker RIP-mediated necroptosis in the intestinal epithelium as a novelpathogenic mechanism in inflammatory bowel disease.
7 Jun 2011 Kristina Endres ADAM10 as a potential target in treatment of Alzheimer’s disease.
31 May 2011 Marcia L. Moss The use of prodomains of ADAM family members to begin investigating proliferation and shedding events of the breast cancer tumor cell line BT474.
10 May 2011 Stefan Lichtenthaler Regulated Intramembrane Proteolysis: from Signal Transduction to Alzheimer’s Disease.
12 Apr 2011 Dominique Soldati-Favre Molecular events governing the lytic cycle in Apicomplexa.
1 Mar 2011 Andreas Ludwig ADAM17 as regulator of leukocyte recruitment and vasula permeability changes within lung inflammation.
8 Feb 2011 Paul Gutwein The role of ADAM10 and its substrate L1-CAM in the progression of cancer.
11 Jan 2011 Thomas Langer Mitochondrial quality control and neurodegeneration.
 
2011 - Invited Speakers for the IRTG Seminars Science Meets Industry
Date Speaker Topic
16 Dec 2011 Michael Badke The Jump of a Molecular Biologist into the World of Marketing and Global Product Management.
17 Jun 2011 Thomas Kernebeck A Patent Lawyer’s Job Description.
18 Feb 2011 Malte Peters Drug-Development of targeted Agent in Cancer.
 
2010 - Invited Speakers for the CRC Seminars
Date Speaker Topic
7 Dec 2010 Peter Vandenabeele Necroptosis, a programmed way for cellular explosion.
9 Nov 2010 Elke Krüger Regulation of degradation capacities of the proteasome in response to changing proteolytic requirements.
18 Aug 2010 Björn Rabe The role of the nuclease RNaseH2 in mammalian development and autoimmune disease.
27 Jul 2010 Karin Müller-Decker COX-2 transgenic mice as models of early-stage-pancreatic cancer.
 
2010 - Invited Speakers in the course of the Visiting Researchers Programme
Date Speaker Topic
26 Oct 2010 Peter Dempsey Role of ADAMs in Intestinal Homeostasis.
 
2010 - Invited Speakers for the IRTG Seminars Science Meets Industry
Date Speaker Topic
22 Oct 2010 Georg Wätzig Crossing the 'Valley of Death' between Academia and the Pharmaceutical Industry - Experiences from a Drug Development Project in Kiel.