Publications of Research Area A4
Regulation and functional relevance of ADAM10 and
ADAM17-mediated proteolysis
Teilprojektleiter: Karina Reiß
- Pore-forming bacterial toxins and antimicrobial peptides as modulators of ADAM function.Reiss K, Bhakdi S. Med Microbiol Immunol. 2012 Nov;201(4):419-26
- Adam10 haploinsufficiency causes freckle-like macules in Hairless mice. Tharmarajah G, Faas L, Reiss K, Saftig P, Young A, Van Raamsdonk CD. Pigment Cell Melanoma Res. 2012 Sep;25(5):555-565.
- Melittin Modulates Keratinocyte Function through P2 Receptor-dependent ADAM Activation. Sommer A, Fries A, Cornelsen I, Speck N, Koch-Nolte F, Gimpl G, Andrä J, Bhakdi S, Reiss K. J Biol Chem. 2012 Jul 6;287(28):23678-89.
- Digestive vacuole of Plasmodium falciparum released during erythrocyte rupture dually activates complement and coagulation. Dasari P, Heber SD, Beisele M, Torzewski M, Reifenberg K, Orning C, Fries A, Zapf AL, Baumeister S, Lingelbach K, Udomsangpetch R, Bhakdi SC, Reiss K, Bhakdi S. Blood. 2012 May 3;119(18):4301-10.
- Digestive vacuoles of Plasmodium falciparum are selectively phagocytosed by and impair killing function of polymorphonuclear leukocytes.Dasari P, Reiss K, Lingelbach K, Baumeister S, Lucius R, Udomsangpetch R, Bhakdi SC, Bhakdi S. Blood. 2011 Nov 3;118(18):4946-56.
- Expression and regulation of murine SPINK12, a potential orthologue of human LEKTI2. Reiss K, Meyer-Hoffert U, Fischer J, Sperrhacke M, Wu Z, Dimitrieva O, Krenek P, Suchanova S, Buryova H, Brauer R, Sedlacek R. Exp Dermatol. 2011 Nov;20(11):905-10
- Unsaturated fatty acids drive disintegrin and metalloproteinase (ADAM)-dependent cell adhesion, proliferation, and migration by modulating membrane fluidity. Reiss K, Cornelsen I, Husmann M, Gimpl G, Bhakdi S. J Biol Chem. 2011 Jul 29;286(30):26931-42.
- Inhibition of kallikrein-related peptidases by the serine protease inhibitor of Kazal-type 6. Kantyka T, Fischer J, Wu Z, Declercq W, Reiss K, Schröder JM, Meyer-Hoffert U. Peptides. 2011 Jun;32(6):1187-92.
- Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17.Maretzky T, Evers A, Zhou W, Swendeman SL, Wong PM, Rafii S, Reiss K, Blobel CP. Nat Commun. 2011;2:229
- IL-1β and ADAM17 are central regulators of β-defensin expression in Candida esophagitis. Pahl R, Brunke G, Steubesand N, Schubert S, Böttner M, Wedel T, Jürgensen C, Hampe J, Schäfer H, Zeissig S, Schreiber S, Rosenstiel P, Reiss K, Arlt A. Am J Physiol Gastrointest Liver Physiol. 2011 Apr;300(4):G547-53
- The "A Disintegrin And Metalloproteases" ADAM10 and ADAM17: novel drug targets with therapeutic potential?Saftig P, Reiss K. Eur J Cell Biol. 2011 Jun-Jul;90(6-7):527-35
- ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site. Le Gall SM, Maretzky T, Issuree PD, Niu XD, Reiss K, Saftig P, Khokha R, Lundell D, Blobel CP. J Cell Sci. 2010 Nov 15;123(Pt 22):3913-22
- Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice. Chalaris A, Adam N, Sina C, Rosenstiel P, Lehmann-Koch J, Schirmacher P, Hartmann D, Cichy J, Gavrilova O, Schreiber S, Jostock T, Matthews V, Häsler R, Becker C, Neurath MF, Reiss K, Saftig P, Scheller J, Rose-John S. J Exp Med. 2010 Aug 2;207(8):1617-24
- MMP19 is upregulated during melanoma progression and increases invasion of melanoma cells. Müller M, Beck IM, Gadesmann J, Karschuk N, Paschen A, Proksch E, Djonov V, Reiss K, Sedlacek R. Mod Pathol. 2010 Apr;23(4):511-21
