Publications of Research Area A5
Molecular mechanisms and functional consequences of
ADAM protease activation induced by extracellular NAD or ATP
Teilprojektleiter: Friedrich Koch-Nolte
- Alternative splicing of the N-terminal cytosolic and transmembrane domains of P2X7 controls gating of the ion channel by ADP-ribosylation. Schwarz N, Drouot L, Nicke A, Fliegert R, Boyer O, Guse AH, Haag F, Adriouch S, Koch-Nolte F. PLoS One. 2012;7(7):e41269
- Melittin modulates keratinocyte function through P2 receptor-dependent ADAM activation.Sommer A, Fries A, Cornelsen I, Speck N, Koch-Nolte F, Gimpl G, Andrä J, Bhakdi S, Reiss K. J Biol Chem. 2012 Jul 6;287(28):23678-89
- Signal-peptide-peptidase-like 2a (SPPL2a) is targeted to lysosomes/late endosomes by a tyrosine motif in its C-terminal tail.Behnke J, Schneppenheim J, Koch-Nolte F, Haag F, Saftig P, Schröder B. FEBS Lett. 2011 Oct 3;585(19):2951-7
- Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding.Garbers C, Jänner N, Chalaris A, Moss ML, Floss DM, Meyer D, Koch-Nolte F, Rose-John S, Scheller J. J Biol Chem. 2011 Apr 29;286(17):14804-11


