Publications of Research Area B2
Proteolysis in the regulation of caspase-independent
programmed cell death
Teilprojektleiter: Dieter Adam / Stefan Schütze
- Lipid-Labeling Facilitates a Novel Magnetic Isolation Procedure to Characterize Pathogen-Containing Phagosomes.Steinhäuser C, Heigl U, Tchikov V, Schwarz J, Gutsmann T, Seeger K, Brandenburg J, Fritsch J, Schroeder J, Wiesmüller KH, Rosenkrands I, Walther P, Pott J, Krause E, Ehlers S, Schneider-Brachert W, Schütze S, Reiling N. Traffic. 2012 Dec 11. doi: 10.1111/tra.12031 [Epub ahead of print]
- Topical application of phosphatidyl-inositol-3,5-bisphosphate for acute lung injury in neonatal swine.Preuss S, Omam FD, Scheiermann J, Stadelmann S, Winoto-Morbach S, von Bismarck P, Adam-Klages S, Knerlich-Lukoschus F, Lex D, Wesch D, Held-Feindt J, Uhlig S, Schütze S, Krause MF. J Cell Mol Med. 2012 Nov;16(11):2813-26
- E3-14.7K is recruited to TNF-receptor 1 and blocks TNF cytolysis independent from interaction with optineurin.Klingseisen L, Ehrenschwender M, Heigl U, Wajant H, Hehlgans T, Schütze S, Schneider-Brachert W. PLoS One. 2012;7(6):e38348
- Inositol-trisphosphate reduces alveolar apoptosis and pulmonary edema in neonatal lung injury.Preuss S, Stadelmann S, Omam FD, Scheiermann J, Winoto-Morbach S, von Bismarck P, Knerlich-Lukoschus F, Lex D, Adam-Klages S, Wesch D, Held-Feindt J, Uhlig S, Schütze S, Krause MF. Am J Respir Cell Mol Biol. 2012 Aug;47(2):158-69
- IKK NBD peptide inhibits LPS induced pulmonary inflammation and alters sphingolipid metabolism in a murine model. von Bismarck P, Winoto-Morbach S, Herzberg M, Uhlig U, Schütze S, Lucius R, Krause MF. Pulm Pharmacol Ther. 2012 Jun;25(3):228-35.
- Functional expression of NOD2 in freshly isolated human peripheral blood γδ T cells. Marischen L, Wesch D, Oberg HH, Rosenstiel P, Trad A, Shomali M, Grötzinger J, Janssen O, Tchikov V, Schütze S, Kabelitz D. Scand J Immunol. 2011 Aug;74(2):126-34.
- Antiapoptotic function of Toso (Faim3) in death receptor signaling.Nguyen XH, Fattakhova G, Lang PA, Lang KS, Adam D, Föger N, Lee KH. Blood. 2012 Feb 16;119(7):1790-1
- Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by Acid sphingomyelinase and transient receptor potential classical 6.Samapati R, Yang Y, Yin J, Stoerger C, Arenz C, Dietrich A, Gudermann T, Adam D, Wu S, Freichel M, Flockerzi V, Uhlig S, Kuebler WM. Am J Respir Crit Care Med. 2012 Jan 15;185(2):160-70
- The enlarged lysosomes in beige j cells result from decreased lysosome fission and not increased lysosome fusion.Durchfort N, Verhoef S, Vaughn MB, Shrestha R, Adam D, Kaplan J, Ward DM. Traffic. 2012 Jan;13(1):108-19
- Toso regulates the balance between apoptotic and non-apoptotic death receptor signaling by facilitating RIP1 ubiquitination.Nguyen, X-H*, Lang, P*, Lang, K*, Adam, D*, Fattakhova, G, Föger, N, Kamal, A, Prilla, P, Mathieu, S, Wagner, C, Mak, T, Chan, AC, Lee, K-H. Blood. 2011 Jul 21;118(3):598-608
*these authors contributed equally to this paper - Compartmentalization of TNF-Receptor 1 Signaling: TNF-R1-Associated Caspase-8 Mediates Activation of Acid Sphingomyelinase in Late Endosomes. Bertsch U, Edelmann B, Tchikov V, Winoto-Morbach S, Schütze S. Adv Exp Med Biol. 2011;691:605-16
- Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes. Edelmann B, Bertsch U, Tchikov V, Winoto-Morbach S, Perrotta C, Jakob M, Adam-Klages S, Kabelitz D, Schütze S. EMBO J. 2011 Jan 19;30(2):379-94
- Subcellular compartmentalization of TNF receptor-1 and CD95 signaling pathways. Tchikov V, Bertsch U, Fritsch J, Edelmann B, Schütze S.Eur J Cell Biol. 2011 Jun-Jul;90(6-7):467-75
- TRAIL signaling is mediated by DR4 in pancreatic tumor cells despite the expression of functional DR5. Lemke J, Noack A, Adam D, Tchikov V, Bertsch U, Röder C, Schütze S, Wajant H, Kalthoff H, Trauzold A. J Mol Med. 2010 Jul;88(7):729-40
- The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase. Philipp S, Puchert M, Adam-Klages S, Tchikov V, Winoto-Morbach S, Mathieu S, Deerberg A, Kolker L, Marchesini N, Kabelitz D, Hannun YA, Schütze S, Adam D. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1112-7
