Dr. rer. nat. Athena Chalaris
Institute of Biochemistry, CAU Kiel
Born 05.03.1979
| 1998–2003 | Studies of Biology, Christian-Albrechts-University Kiel |
| 2003–2004 | Master thesis, Center for Molecular Neurobiology, UKE Hamburg |
| 2004–2007 | Doctoral thesis Biochemical Institute, Christian-Albrechts-University Kiel |
| 2008 | Scientist, Biochemical Institute, Christian-Albrechts-University Kiel |
Selected Publications
- Drucker C, Rabe B, Chalaris A, Schulz E, Scheller J, Rose-John S. (2009) Interleukin-6 Trans- Signaling Regulates Glycogen Consumption After d-Galactosamine-Induced Liver Damage. J Interferon Cytokine Res, in press
- Plagmann I, Chalaris A, Kruglov AA, Nedospasov S, Rosenstiel P, Rose-John S, Scheller J. (2009) Transglutaminase-catalyzed covalent multimerization of Camelidae anti-human TNF single domain antibodies improves neutralizing activity. J Biotechnol 142: 170-178
- Tenhumberg S, Waetzig GH, Chalaris A, Rabe B, Seegert D, Scheller J, Grötzinger J. (2008) Structure guided optimization of the interleukin-6 transsignaling antagonist sgp130. J Biol Chem 283: 27200-27207
- Rabe B, Chalaris A, May U, Waetzig GH, Seegert D, Williams AS, Jones SA, Rose-John S, Scheller J. (2008) Transgenic blockade of Interleukin-6-trans-signaling abrogates inflammation. Blood 111: 1021-1028
- Chalaris A, Rabe B, Paliga K, Lange H, Laskay T, Fielding CA, Jones SA, Rose-John S, Scheller J. (2007) Apoptosis is a natural stimulus of IL-6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils. Blood 110: 1748-1755
- Stuhlmann-Laeisz C, Lang S, Chalaris A, Paliga K, Enge S, Eichler J, Klingmüller U, Samuel M, Ernst M, Rose-John S, Scheller J. (2006) Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells. Mol Biol Cell 17: 2986-2995
