Prof. Dr. rer. nat. Joachim Grötzinger
Institute of Biochemistry, CAU Kiel
Born 09. 05. 1957
| 1977–1979 | Studies of Chemistry, Bergischen Universität Gesamthochschule Wuppertal |
| 1979–1985 | Studies of Chemistry, RWTH Aachen |
| 1989 | Research visit at Daresbury, SERC Daresbury Laboratory, Warrington, UK |
| 1985–1990 | Dissertation at (summa cum laude), Institute of Biochemistry, RWTH Aachen |
| 1991–1992 | Research Associate, Institute of Biophysical Chemistry, University Groningen, NL |
| 1992–2001 | Scientific Assistant, Department of Biochemistry, RWTH Aachen |
| 1998 | Habilitation in Physical Biochemistry RWTH Aachen |
| Since 2001 | Senior researcher at the Biochemical Institute, Christian-Albrechts-Universität zu Kiel |
| 2005 | apl. Professor |
10 Selected Publications
- Drechsler, J., Grötzinger, J., Hermanns, H.M. Rat Oncostatin M equals human Oncostatin M by signaling via the type I gp130/LIFR as well as the type II gp130/OSMR complex. Plos One 7, e43155 (2012)
- Bosch TCG, Augustin R, Anton-Erxleben F, Fraune S, Hemmrich G, Zill H, Rosenstiel P, Jacobs G, Schreiber S, Leippe M, Stanisak M, Grötzinger J, Jung S, Podschun R, Bartels J, Harder J, Schröder JM. (2009) Uncovering the evolutionary history of innate immunity: the simple metazoan hydra uses epithelial cells for host defence. Dev Comp Immun 33: 559-569
- Adam N, Rabe B, Suthaus J, Grötzinger J, Rose-John S, Scheller J. (2009) Understanding receptor independent gp130 activation by viral interleukin-6. J Virol 83: 5117-5126
- Michalek M, Gelhaus C, Hecht O, Podschun R, Schröder JM, Leippe M, Grötzinger J. (2009) The human antimicrobial protein Psoriasin acts by permeabilization of bacterial membranes. Dev Comp Immun 33: 740-746
- Jung S, Dingley AJ, Augustin R, Anton-Erxleben F, Stanisak M, Gelhaus C, Gutsmann T, Hammer MU, Podschun R, Leippe M, Bosch TCG, Grötzinger J. (2009) Hydramacin-1: Structure and antibacterial activity of a peptide from the basal metazoan Hydra. J Biol Chem 284: 1896–1905
- Tenhumberg S, Waetzig GH, Chalaris A, Rabe B, Seegert D, Scheller J, Rose-John, S, Grötzinger J. (2008) Structure guided optimization of the interleukin-6 transsignalling antagonist sgp130. J Biol Chem 283: 27200–27207
- Bruhn O, Regenhard P, Michalek M, Paul S, Gelhaus C, Jung S, Thaller G, Podschun R, Leippe M, Grötzinger J, Kalm E. (2007) A novel -defensin of the horse: gene transcription, recombinant expression and characterization of the structure and function. Biochem J 407: 267- 276
- Krone N, Grischuk Y, Müller M, Volk RE, Grötzinger J, Holterhus PM, Sippell WG, Riepe FG. (2006) Analyzing the functional and structural consequences of two point mutations (P94L, A368D) in the CYP11B1 gene causing congenital adrenal hyperplasia (CAH) due to 11- hydroxylase deficiency. J Clin Endocrinol Metab. 91: 2682-2688
- Lorenzen I, Dingley AJ, Jacques Y, Grötzinger J. (2006) The structure of the IL-15a-receptor and its implications for ligand binding. J Biol Chem 281: 6642–6647
- Röderfeld M, Weiskirchen R, Wagner S, Berres ML, Henkel C, Grötzinger J. Gressner AM, Matern S, Roeb E. (2006) Inhibition of hepatic fibrogenesis by MMP-9 mutants in mice. FASEB J 20: 444-454
