Prof. Dr. med. Stefan Schreiber
Institut für Klinische Molekularbiologie, CAU Kiel
Born 25. 06. 1962
| 1987–1988 | Assistant Physician University of Hamburg |
| 1988–1990 | Research Associate, Washington University School of Medicine, Division of Gastroenterology |
| 1990–1991 | Research Associate, University of Pennsylvania School of Medicine |
| 1991–1994 | Assistant Physician, University of Hamburg |
| 1994–1998 | Faculty at the Charité University Hospital (Humboldt University), IVth Medical Department (Director: Prof. Dr. H. Lochs) |
| 1996 | Habilitation in Internal Medicine at the Charité University Hospital |
| 1998–2004 | Frederik Paulsen Professor (C3) for Medicine and Gastroenterology at the Christian-Albrechts University in Kiel |
| Since Dec 2004 | Christian-Albrechts-University zu Kiel, Head of the Institute of Clinical Molecular Biology (C4), Head of the section Luminal Gastroenterology, University Hospital |
| Since May 2009 | Director Clinic for Internal Medicine I, University Hospital Schleswig-Holstein |
10 Selected Publications
- Flachsbart F, Caliebe A, Kleindorp R, Blanche H, von Eller-Eberstein H, Nikolaus S, Schreiber S, Nebel A. (2009) Association of FOXO3A variation with human longevity confirmed in German centenarians. Proc Natl Acad Sci U S A 106: 2700-2705
- Hofmann S, Franke A, Fischer A, Jacobs G, Nothnagel M, Gaede KI, Schurmann M, Muller- Quernheim J, Krawczak M, Rosenstiel P, Schreiber S. (2008) Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis. Nat Genet 40: 1103-1106
- Kaser A, Lee AH, Franke A, Glickman JN, Zeissig S, Tilg H, Nieuwenhuis EE, Higgins DE, Schreiber S, Glimcher LH, Blumberg RS. (2008) XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell 134: 743- 756
- Franke A, Balschun T, Karlsen TH, Hedderich J, May S, Lu T, Schuldt D, Nikolaus S, Rosenstiel P, Krawczak M, Schreiber S. (2008) Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis. Nat Genet 40: 713-715
- Franke A, Balschun T, Karlsen TH, Sventoraityte J, Nikolaus S, Mayr G, Domingues FS, Albrecht M, Nothnagel M, Ellinghaus D, Sina C, Onnie CM, Weersma RK, Stokkers PC, Wijmenga C, Gazouli M, Strachan D, McArdle WL, Vermeire S, Rutgeerts P, Rosenstiel P, Krawczak M, Vatn MH, Mathew CG, Schreiber S. (2008) Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat Genet 40: 1319-1323
- Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, Albrecht M, Mayr G, De La Vega FM, Briggs J, Gunther S, Prescott NJ, Onnie CM, Hasler R, Sipos B, Folsch UR, Lengauer T, Platzer M, Mathew CG, Krawczak M, Schreiber S. (2007) A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 39: 207-211
- Schreiber S, Khaliq-Kareemi M, Lawrance IC, Østergaard Thomsen O, Hanauer SB, McColm J, Bloomfield R, Sandborn WJ. (2007) Certolizumab Pegol Maintenance Therapy for Crohn’s Disease. New Engl J Med 357: 228-238
- Rosenstiel P, Huse K, Till A, Hampe J, Hellmig S, Sina C, Billmann S, von Kampen O, Waetzig GH, Platzer M, Seegert D, Schreiber S. (2006) A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways. Proc Natl Acad Sci U S A 103: 3280-3285
- Valentonyte R, Hampe J, Huse K, Rosenstiel P, Albrecht M, Stenzel A, Nagy M, Gaede KI, Franke A, Haesler R, Koch A, Lengauer T, Seegert D, Reiling N, Ehlers S, Schwinger E, Platzer M, Krawczak M, Muller-Quernheim J, Schurmann M, Schreiber S. (2005) Sarcoidosis is associated with a truncating splice site mutation in BTNL2. Nat Genet 37: 357-364
- Nikolaus S, Albrecht M, Hampe J, Lucius R, Kloppel G, Eickhoff H, Lehrach H, Lengauer T, Schreiber S. (2005) Dissection of the inflammatory bowel disease transcriptome using genomewide cDNA microarrays. PLoS Med 2: e199
