|
2012
Kayser O, Osmonov D, Harde J, Girolami G, Wedel T, Schäfer P (2012) Less invasive causal treatment of ejaculatory duct obstruction by balloon dilation: a case report, literature review and suggestion of a CT- or MRI-guided intervention. GMS German Medical Science 10:1-8
Wedel T, Barrenschee M, Hellwig I, Harde J, Böttner M (2012) Pathogenesis of diverticulosis and diverticular disease of the colon. Viszeralmedizin 28:164-70
Böttner M, Wedel T (2012) Abnormalities of neuromuscular anatomy in diverticular disease. Dig Dis 30:19-23
Böttner M, Zorenkov D, Hellwig I, Barrenschee M, Harde J, Fricke T, Deuschl G, Egberts JH, Becker T, Fritscher-Ravens A, Arlt A, Wedel T (2012) Expression pattern and localization of alpha-synuclein in the human enteric nervous system. Neurobiol Dis 48:474-80
Böttner M, Barrenschee M, Hellwig I, Harde J, Egberts JH, Becker T, Zorenkov D, Wedel T (2012) The enteric serotonergic system is altered in patients with diverticular disease. Gut 27
Fritscher-Ravens A, Milla P, Ellrichmann M, Hellwig I, Böttner M, Hadeler KG, Wedel T (2012) A novel endoscopic prototype device for gastric full-thickness biopsy for the histopathological diagnosis of GI neuromuscular pathology: in vivo porcine long-term survival study (with videos). Gastrointest Endosc 27
2011
Pahl R, Brunke G, Steubesand N, Schubert S, Böttner M, Wedel T, Jürgensen C, Hampe J, Schäfer H, Zeissig S, Schreiber S, Rosenstiel P, Reiss K, Arlt A (2011) IL-1β and ADAM17 are central regulators of β-defensin expression in Candida esophagitis. Am J Physiol Gastrointest Liver Physiol 300:G547-53
Knowles CH, Veress B, Kapur RP, Wedel T, Farrugia G, Vanderwinden JM, Geboes K, Smith VV, Martin JE, Lindberg G, Milla PJ, De Giorgio R (2011) Quantitation of cellular components of the enteric nervous system in the normal human gastrointestinal tract. Report on behalf of the Gastro 2009 International Working Group. Neurogastroentrol Motil 23:115-24
Petto C, Lesko S, Gäbel G, Böttner M, Wedel T, Kacza J, Pfannkuche H (2011) Establishment and characterisation of porcine colonic epithelial cells grown in primary culture. Cells Tissue Organs 194:457-68
Keller J, Wedel T, Seidl H, Kreis ME, Andresen V, Preiß JC, Layer P, van der Voort I (2011) S3-Leitlinie der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Neurogastroenterologie und Motilität (DGNM) zu Definition, Pathophysiologie, Diagnostik und Therapie intestinaler Motilitätsstörungen. Z Gastroenterol 49: 374-390
Stelzner S, Holm T, Moran BJ, Heald RJ, Witzigmann H, Zorenkov D, Wedel T (2011) Deep pelvic anatomy revisited for a description of crucial steps in extralevator abdominoperineal excision for rectal cancer. Dis Colon Rectum 54:947-57
Van Landeghem L, Chevalier J, Mahé MM, Wedel T, Urvil P, Derkinderen P, Savidge TC, Neunlist M (2011) Enteric glia promotes intestinal mucosal healing via activation of focal adhesion kinase and release of ProEGF. Am J Physiol Gastrointest Liver Physiol 300:G976-87
Zorenkov D, Otto S, Böttner B, Hedderich J, Vollrath O, Peter JP, Buhr H, Wedel T (2011) Morphological alterations of the enteric nervous system in young male patients with rectal prolapse. Int J Colorectal Dis 26:1483-91
2010
Böttner M, Leonhardt S, Wuttke W, Wedel T, Jarry H (2010) Expression of estrogen receptors in the hypothalamo-pituitary-ovarian axis in middle-aged rats after re-instatement of estrus cyclicity. Biogerontol 11:75-85 (IF=3,6)
Böttner M, Bär F, von Koschitzky H, Tafazzoli K, Roblick UJ, Bruch HP, Wedel T (2010) Laser microdissection as a new tool to investigate site-specific gene expression in enteric ganglia of the human intestine. Neurogastroenterol Motil 22:168-72
Wedel T, Büsing V, Heinrichs G, Nohroudi K, Bruch HP, Roblick U, Böttner M (2010): Diverticular disease is associated with an enteric neuropathy as revealed by morphometric analysis. Neurogastroenterol Motil 22:407-14
Knowles CH, De Giorgio R, Kapur RP, Bruder E, Farrugia G, Geboes K, Lindberg G, Martin JE, Meier-Ruge WA, Milla PJ, Smith VV, Vandervinden JM, Veress B, Wedel T (2010) The London classification of gastrointestinal neuromuscular pathology (GINMP): report on behalf of the Gastro 2009 International Working Group. Gut 59:882-7
2009
Teixeira AF, Kühnel W, Vives P, Wedel T (2009). Functional
morphology of unguiculiform papillae of the reticular groove in
the ruminant stomach. Ann Anat 191:469-76.
Knowles CH, De Giorgio R, Farrugia G, Geboes K, Gershon MD, Hutson
J, Kapur RP, Lindberg G, Martin JE, Milla PJ, Smith VV, Veress
B, Wedel T (2009) Gastrointestinal neuromuscular pathology: guidelines
for histological techniques and reporting on behalf of the Gastro
2009 International Working Group. Acta Neuropatho 118:271-301
Neunlist M, Coron E, Flamant M, Aubert P, Wedel T, Pedron T, Letessier
E, Galmiche JP, Sansonetti PJ (2009) Characterisation of early
mucosal and neuronal lesions following Shigella flexneri infection
in human colon. PLoS ONE 4(3):e4713
Bär F, von Koschitzky H, Roblick U, Bruch HP, Schulze L,
Sonnenborn U, Böttner M, Wedel T (2009): Cell-free supernatants
of Escherichia coli Nissle 1917 (EcN) modulate human colonic motility
- evidence from an in-vitro organ bath study (2009) Neurogastroenterol
Motil 21:559-66
Spanholtz T, Maichle A, Niedworok C, Stoeckelhuber BM, Krüger
S, Wedel T, Aach T, Middeler G, Hellwig-Bürgel T, Bader A,
Krengel S, Müller OJ, Franz WM, Lindenmaier W, Machens HG
(2009) Timing and targeting of cell-based VEGF(165) gene expression
in ischemic tissue. J Surg Res 151:153-62
2008
Böttner M, Christoffel J, Wuttke W. (2008) Effects
of long-term treatment with 8-prenylnaringenin and oral estradiol
on the GH-IGF-1 axis and lipid metabolism in rats. J Endocrinol.
198: 395-401
Aigner F, Gruber H, Conrad F, Eder J, Wedel T, Zelger B, Engelhardt
V, Lametschwandtner A, Wienert V, Böhler U, Margreiter R,
Fritsch H: Revised morphology and hemodynamics of the anorectal
vascular plexus: Impact on the course of hemorrhoidal disease.
Int J Colorectal Dis 24:105-13
Jacobsen HC, Hakim SG, Lauer I, Dendorfer A, Wedel T, Sieg P (2008)
Long-term results of autologous submandibular gland transfer for
the surgical treatment of severe keratoconjunctivitis sicca. J
Craniomaxillofac Surg 36: 227-233
Harloff S, Hartwig D, Kasper K, Wedel T, Müller M, Geerling
G (2008): Epitheliotrophic Capacity of Serum Eye Drops from Healthy
Donors versus Serum from Immunosuppressed Patients with Rheumatoid
Arthritis. Klin Monatsbl Augenheilkd 225: 200-206
Farke S, Paech A, Duchrow M, Bethge T, Wedel T, Lindner B, Roblick
UJ, Bruch HP, Broll R (2008): Re-Sterilization of Surgical Polypropylene
Meshes: Should it be Done? Research Journal of Medical Science
2: 7-12
2007
Böttner M, Leonhardt S, Wuttke W, Jarry H (2007)
Changes of expression of genes related to the activity of the
gonadotrophin-releasing hormone pulse generator in young versus
middle-aged male rats. J Neuroendocrinol. 19:779-787.
Suzuki S, Gerhold LM, Böttner M, Rau SW, Dela Cruz C, Yang
E, Zhu H, Yu J, Cashion AB, Kindy MS, Merchenthaler I, Gage FH,
Wise PM (2007) Estradiol enhances neurogenesis following ischemic
stroke through estrogen receptors alpha and beta. J Comp Neurol
500; 1064-1075.
Wedel T (2007) Functional Anatomy - Prerequisite for the understanding
of defecation disorders. Chir Gastroenterol 23: 220-227
Wedel T, Böttner M, Krammer HJ (2007) The enteric nervous
system and interstitial cells of Cajal. Changes in chronic constipation
in adults. Pathologe 28:143-148
Schrader S, Wedel T, Kremling C, Laqua H, Geerling G (2007) Amniotic
membrane as a carrier for lacrimal gland acinar cells. Graefes
Arch Clin Exp Ophthalmol 245: 1699-704
Hernando-Harder AC, Franke A, Wedel T, Bottner M, Krammer HJ,
Singer MV, Harder H (2007) Intestinal Gas Retention in Patients
with Idiopathic Slow-Transit Constipation. Dig Dis Sci 52: 2667-75
Beutel J, Schroder C, von Hof K, Rades D, Kosmehl H, Wedel T,
Sieg P, Geerling G, Hakim S (2007) Pharmacological prevention
of radiation-induced dry eye - An experimental study in a rabbit
model. Graefes Arch Clin Exp Ophthalmol 245: 1347-55
Neunlist M, Aubert P, Bonnaud S, van Landeghem L, Coron E, Wedel
T, Naveilhan P, Ruhl A, Lardeux B, Savidge T, Paris F, Galmiche
JP (2007) Enteric glia inhibits intestinal epithelial cell proliferation
partly through a TGF-ß1-dependent pathway. Am J Physiol
Gastrointest Liver Physiol 292: 231-241
Kohl M, Wedel T, Entenmann A, Stuttmann J, Bendiks M, Loff S,
Koster S, Ortfeld S, Bos I (2007) Influence of different intravenous
lipid emulsions on hepatobiliary dysfunction in a rabbit model.
J Pediatr Gastroenterol Nutr 44: 237-44
2006
Trauzold A, Siegmund D, Schniewind B, Sipos B, Egberts J, Zorenkov
D, Emme D, Röder C, Kalthoff H, Wajant H (2006) TRAIL promotes
metastasis of human pancreatic ductal adenocarcinoma. Oncogene
25:7434-9.
von Schassen C, Fester L, Prange-Kiel J, Lohse C, Huber C, Böttner
M, Rune GM (2006) Oestrogen synthesis in the hippocampus: role
in axon outgrowth. J Neuroendcrinol 18: 847-856.
Böttner M, Wuttke W. (2006) Chronic treatment with physiological
doses of estradiol affects the GH-IGF-1 axis and fat metabolism
in young and middle-aged ovariectomized rats. Biogerontology 7:
91-100.
Böttner M, Christoffel J, Jarry H, Wuttke W. (2006) Effects
of long-term treatment with resveratrol and subcutaneous and oral
estradiol administration on pituitary function in rats. J Endocrinol
189:77-88.
Fester L, Ribeiro-Gouveia V., Prange-Kiel J, von Schassen C, Böttner
M, Jarry H, Rune GM (2006) Proliferation and apoptosis of hippocampal
granule cells require local oestrogen synthesisl J. Neurochem
97:1136-1144.
Böttner M, Christoffel J, Rimoldi G, Wuttke W. (2006) Effects
of long-term treatment with resveratrol and subcutaneous and oral
estradiol administration on the pituitary-thyroid axis. Exp Clin
Endocrinol Diabetes 114:82-90.
Dubal DB, Rau SW, Shughrue PJ, Zhu H, Yu J, Cashion AB, Suzuki
G, Gerhold LM, Böttner M, Dubal SB, Merchanthaler I, Kindy
MS, Wise PM. (2006) Differential modulation of estrogen receptors
(ERs) in ischemic brain injury: a role for ERalpha in estradiol-mediated
protection against delayed cell death. Endocrinology 147: 3076-3084.
Kruse C, Kajahn J, Petschnik AE, Maass A, Klink E, Rapoport DH,
Wedel T (2006) Adult pancreatic stem/progenitor cells spontaneously
differentiate in vitro into multiple cell lineages and form teratoma-like
structures. Ann Anat 188: 503-517
Schrader S, Wedel T, Moll R, Geerling G (2006) Combination of
serum eye drops with hydrogel bandage contact lenses in the treatment
of persistent epithelial defects. Graefes Arch Clin Exp Ophthalmol
244: 1345-1349
Wedel T (2006) Der Beckenboden: Anatomische Grundlagen. Viszeralchirurgie
41: 153-162
Wedel T, van Eys G, Glénisson W, Waltregny D, Vanderwinden
JM (2006) Novel smooth muscle markers reveal abnormalities of
the intestinal musculature in severe colorectal motility disorders.
Neurogastroenterol Motil 18: 526-538
Liu L, Hartwig D, Harloff S, Herminghaus P, Wedel T, Geerling
G (2006) Corneal epitheliotrophic capacity of three different
blood-derived preparations. Invest Ophtamol Vis Sci 47: 2438-2444
Nishino T, Wedel T, Schmitt O, Bühlmeyer K, Schönfelder
M, Hirtreiter C, Schulz T, Kühnel W, Michna H (2006) The
xenoestrogen bisphenol A in the Hershberger assay: androgen receptor
regulation and morphometrical reactions indicate no major effects.
J Steroid Biochem Mol Biol 98: 155-163
Hakim S, Schroder C, Geerling G, Lauer I, Wedel T, Kosmehl H,
Driemel O, Jacobsen HC, Trenkle T, Hermes D, Sieg (2006) Early
and late immunohistochemical and ultrastructural changes associated
with functional impairment of the lacrimal gland following external
beam radiation. Int J Exp Pathol 87: 65-71
2005
Böttner M, Dubal DB, Rau SW, Suzuki S, Wise PM. (2005) Stroke
injury in rats causes an increase in activin A gene expression
which is unaffected by estradiol treatment. J Neuroendocrinol.
18: 97-103.
Böttner M, Wuttke W (2005). Chronic treatment with low doses
of estradiol affects pituitary and thyroid function in middle-aged
ovariectomized rats. Biogerontology 6: 261-269.
Hakim S, Kosmehl H, Lauer I, Nadrowitz R, Wedel T, Sieg P (2005)
A comparative study on the protection profile of lidocaine, amifostine
and pilocarpine on the parotid gland during radiotherapy. Cancer
Res 65: 10486-10493
Niessen P, Rensen S, van Deursen J, De Man J, De Laet A, Vanderwinden
JM, Wedel T, Baker D, Doevendans P, Hofker M, Gijbels M, van Eys
G (2005) Smoothelin-A is essential for functional intestinal smooth
muscle contractility in mice. Gastroenterology 129: 1592-1601
de Lorijn F, de Jonge WJ, Wedel T, Vanderwinden JM, Benninga MA,
Boeckxstaens GE (2005) Interstitial cells of Cajal are involved
in the afferent limb of the rectoanal inhibitory reflex. Gut 54:
1107-13
Tafazzoli K, Soost K, Wessel L, Wedel T (2005) Topographic pecularities
of the submucous plexus in the human anorectum - consequences
for histopathologic evaluation of rectal biopsies. Eur J Pediatr
Surg 15: 159-63
Liu L, Hartwig D, Harloff S, Herminghaus P, Wedel T, Geerling
G (2005) An optimised protocol for the production of autologous
serum eyedrops. Graefes Arch Clin Exp Ophthalmol 243: 706-714
Wedel T (2005) Obstipation. Coloproctology 27: 204-208
Sayk F, Bos I, Schubert U, Wedel T, Sievers HH (2005) Histopathologic
findings in a novel decellularized pulmonary homograft: an autopsy
study. Ann Thorac Surg 79: 1755-8
Tiedemann K, Sasaki T, Gustafsson E, Göhring W, Bätge
B, Notbohm H, Wedel T, Schlötzer-Schrehardt U, Reinhardt
DP (2005). Microfibrils at basement membrane zones interact with
perlecan via fibrillin-1. J Biol Chem 25: 11404-12
Hartwig D, Herminghaus D, Wedel F, Schlenke P, Geerling G (2005)
Topical treatment of ocular surface defects: Comparison of the
epitheliotrophic capacity of fresh frozen plasma and serum on
corneal epithelial cells in an in-vitro cell culture model. Transfusion
Med 15: 107-113
Most P, Boerries M, Eicher C, Schweda C, Wedel T, Söllner
S, Katus HA, Remppis A, Aebi U, Koch WJ, Schoenenberger CA (2005).
Distinct subcellular location of the Ca2+-binding protein S100A1
differentially modulates Ca2+-cycling in ventricular rat cardiomyocytes.
J Cell Science 118:421-31
2004
Bruch HP, Schwandner O, Krammer HJ, Söllner S, Wedel T (2004)
Ursachen und Therapie des Megakolons beim Erwachsenen. Chir Praxis
62, 605-617
Hartwig D, Harloff S, Liu L, Schlenke P, Wedel T, Geerling G (2004)
Epitheliotrophic capacity of a growth factor preparation produced
from platelet concentrates on corneal epithelial cells: A potential
agent for the treatment of ocular surface defects? Transfusion
44: 1724-31
Birth M, Wedel T, Hildebrand P, Bruch HP, Kruse C (2004) Isolation,
culture and characterization of adult pluripotent stem cells of
pancreas. Chir Forum 33: 405-407
Herminghaus P, Hartwig D, Wedel T, Dibbelt L, Geerling G (2004)
Epitheliotrophic capacity of serum and plasma eyedrops. Influence
of centrifugation. Ophtalmologe 101: 998-1005
Holland-Cunz S, Bainczyk S, Hagl C, Wink E., Wedel T, Back W,
Schäfer KH (2004) Three dimensional co-culture model of enterocytes
and primary enteric neuronal tissue. Pediatr Surg Internat 20:
233-7
Nishino T, Wedel T, Schmitt O, Bühlmeyer K, Schönfelder
M, Hirtreiter C, Schulz T, Kühnel W, Michna H (2004) Androgen-dependent
morphology of prostate and seminal vesicles in the Hershberger
Assay: Evaluation of immunohistochemical and morphometric parameters.
Ann Anat 186: 247-253
Kruse C, Birth M, Rohwedel J, Assmuth K, Göpel A, Wedel T
(2004) Pluripotency of adult stem cells derived from human and
rat pancreas. Appl Phys A
2003
Rau SW, Dubal DB, Böttner M, Gerhold LM, Wise PM. (2003)
Estradiol attenuates programmed cell death after stroke-like injury.
J Neurosci. 23:11420-11426.
Rau SW, Dubal DB, Böttner M, Wise PM. (2003) Estradiol differentially
regulates c-Fos after focal cerebral ischemia. J Neurosci. 23:10487-10494.
Wulf J, Busch LC, Wedel T (2003) Anatomie der Leber - vom Orakel
zum dreidimensionalen Modell. Focus MUL 20: 237-240
Holland-Cunz S, Krammer HJ, Süss A, Tafazzoli K, Wedel T
(2003) Molecular genetics of colorectal motility disorders. Eur
J Pediatr Surg 13, 146-151
Wedel T, Tafazzoli K, Söllner S, Krammer HJ, Holschneider
AM (2003) Mitochondrial myopathy (complex I deficiency) associated
with chronic intestinal pseudoobstruction. Eur J Pediatr Surg
13, 201-205
2002
Wise PM, Smith MJ, Dubal DB, Wilson ME, Rau SW, Cashion AB, Böttner
M, Rosewell KL. (2002) Neuroendocrine modulation and repercussions
of female reproductive aging. Recent Prog Horm Res. 57:235-256.
Review.
Krammer HJ, Süss A, Singer MV, Wedel
T (2002) Neurogastroenterology - From the Basics to the Clinics.
R J Gastroenterology 11, 313-319
Wedel T, Spiegler J, Söllner S, Roblick
UJ, Schiedeck THK, Bruch HP, Krammer HJ (2002) Interstitial cells
of Cajal and the enteric nervous system are concomitantly altered
in patients with slow-transit constipation and megacolon. Gastroenterology
123: 1459-1467
Hakim S, Kossmehll H, Lauer I, Nadrowitz R,
Wedel T, Sieg P (2002). The role of myoepithelial cells in the
short-term radiogenic impairment of salivary glands. An immunohistochemical,
ultrastructural and scintigraphic study. Anticancer Res 22: 4121-4128
Von Boyen GBT, Krammer HJ, Dembowski C, Ehrenreich
H, Wedel T (2002) Abnormalities of the enteric nervous system
in heterozygous endothelin B-receptor deficient (spotting lethal)
rats resembling intestinal neuronal dysplasia. Gut 51: 414-419
Wedel T, Roblick UJ, Ott V, Eggers R, Schiedeck
THK, Krammer HJ, Bruch HP (2002) Oligoneuronal hypoganglionosis
in patients with idiopathic slow transit constipation. Dis Colon
Rectum 45: 54-62
2001
Wise PM, Dubal DB, Wilson ME, Rau SW, Böttner M, Rosewell
KL. (2001) Estradiol is a protective factor in the adult and aging
brain: understanding of mechanisms derived from in vivo and in
vitro studies. Brain Res Brain Res Rev. 37(1-3):313-319. Review.
Schober A, Böttner M, Strelau J, Kinscherf R, Bonaterra GA,
Barth M, Schilling L, Fairlie WD, Breit SN, Unsicker K. (2001)
Expression of growth differentiation factor-15/ macrophage inhibitory
cytokine-1 (GDF-15/MIC-1) in the perinatal, adult, and injured
rat brain. J Comp Neurol. 439(1):32-45.
Roosen A, Schober A, Strelau J, Böttner M, Faulhaber J, Bendner
G, McIlwrath SL, Seller H, Ehmke H, Lewin GR, Unsicker K. (2001)
Lack of neurotrophin-4 causes selective structural and chemical
deficits in sympathetic ganglia and their preganglionic innervation.
J Neurosci. 21(9):3073-3084.
Teixera AF, Krammer HJ, Kühnel W, Wedel T (2001) Structural
organisation of the enteric nervous system in the cattle esophagus
revealed by wholemount immunohistochemistry. It J Anat Embryol
106: 313-321
2000
Strelau J, Böttner M, Lingor P, Suter-Crazzolara C, Galter
D, Jaszai J, Sullivan A, Schober A, Krieglstein K, Unsicker K.
(2000) GDF-15/MIC-1 a novel member of the TGF-beta superfamily.J
Neural Transm Suppl. (60):273-276. Review.
Wise PM, Dubal DB, Wilson ME, Rau SW, Böttner M. (2000) Minireview:
neuroprotective effects of estrogen-new insights into mechanisms
of action. Endocrinology. 142(3):969-973. Review.
Böttner M, Krieglstein K, Unsicker K. (2000) The transforming
growth factor-betas: structure, signaling, and roles in nervous
system development and functions. J Neurochem. 75(6):2227-2240.
Review.
Strelau J, Sullivan A, Böttner M, Lingor P, Falkenstein E,
Suter-Crazzolara C, Galter D, Jaszai J, Krieglstein K, Unsicker
K. (2000) Growth/differentiation factor-15/macrophage inhibitory
cytokine-1 is a novel trophic factor for midbrain dopaminergic
neurons in vivo. J Neurosci. 20(23):8597-8603.
Wedel T, Spiegler J, Ott V, Kühnel W, Sigge W, Reusche E,
Krammer HJ (2000) Intestinale Innervationsstörungen bei chronischer
Obstipation. Focus MUL 17: 233-240
Wedel T (2000) Mögliche Ursachen der chronischen Obstipation.
Zentralbl Chir 125:564-566
Wedel T, Roblick UJ, Schiedeck THK, Bruch HP, Reusche E (2000)
Erworbene Hypoganglionose als Folge einer enterischen Ganglionitis.
Focus MUL 17: 246-248
1999
Wedel T, Roblick UJ, Quoß J, Schiedeck THK, Bruch HP, Krammer
HJ (1999) Intestinale Innervationsstörungen: Anatomische
Grundlagen und Diagnostik. Coloproctology 21: 101-108
Wedel T, Eggers R, Gleiß J, Schiedeck THK, Bruch HP, Sigge
W, Krammer HJ (1999) Das enterische Nervensystem: Von der Anatomie
zur Klinik. Focus MUL 16: 22-30
Böttner M, Laaff M, Schechinger B, Rappold G, Unsicker K,
Suter-Crazzolara C. (1999) Characterization of the rat, mouse,
and human genes of growth/differentiation factor-15/macrophage
inhibiting cytokine-1 (GDF-15/MIC-1). Gene. 237(1):105-111.
Böttner M, Suter-Crazzolara C, Schober A, Unsicker K. (1999)
Expression of a novel member of the TGF-beta superfamily, growth/differentiation
factor-15/macrophage-inhibiting cytokine-1 (GDF-15/MIC-1) in adult
rat tissues. Cell Tissue Res. 297(1):103-110.
Galter D, Böttner M, Krieglstein K, Schomig E, Unsicker K.
(1999) Differential regulation of distinct phenotypic features
of serotonergic neurons by bone morphogenetic proteins. Eur J
Neurosci. 11(7):2444-2452.
Galter D, Böttner M, Unsicker K. (1999) Developmental regulation
of the serotonergic transmitter phenotype in rostral and caudal
raphe neurons by transforming growth factor-betas. J Neurosci
Res. 56(5):531-538.
Leffler A, Wedel T, Busch LC (1999) Congenital colonic hypoganglionosis
in murine trisomy 16 - a model for Down´s syndrome. Eur
J Pediatr Surg 9: 381-388
Wedel T, Roblick UJ, Schiedeck THK, Bruch HP, Krammer HJ (1999)
Ist die Divertikelkrankheit mit intestinalen Innervationsstörungen
assoziiert? Viszeralchirurgie 34: 307-311
Wedel T, Roblick UJ, Gleiß J, Ott V, Eggers R, Kühnel
W, Krammer HJ (1999) Intestinale Innervationsstörungen als
mögliche Ursache der chronischen Obstipation. Zentralbl Chir
124: 796-803
Wedel T, Roblick UJ, Gleiß J, Schiedeck THK, Bruch HP, Kühnel
W, Krammer HJ (1999) Organization of the enteric nervous system
in the human colon demonstrated by wholemount immunohistochemistry
with special reference to the submucous plexus. Ann Anat 181:
327-337
Michailova K, Wassilev W, Wedel T (1999) Scanning and transmission
electron microscopic study of visceral and parietal peritoneal
regions in the rat. Ann Anat 181: 253-260
Entenmann A, Wedel T, Kolbert G, Bruch HP, Kühnel W (1999)
Morphologische Untersuchungen zur alloplastischen Deckung von
Bauchwanddefekten. Focus MUL 16: 148-154
Entenmann A, Wedel T, Kolbert G, Kühnel W, Bruch HP (1999)
Scanning electron microscopy study including maceration techniques
of an absorbable alloplastic implant designed for the reconstruction
of ventral abdominal wall defects. Ann Anat 181: 237-245
Wedel T, Holschneider AM, Krammer HJ, Kühnel W (1999) Ultrastructural
features of nerve fascicles and basal lamina abnormalities in
Hirschsprung´s disease. Eur J Ped Surg 9: 75-82 |
|
2012
Wedel T (2012) Anatomy of the rectum, anal canal and pelvic floor. In Moran B, Heald RJ (eds.) Manual of Total Mesorectal Excision. Hodder Arnold´s Publishers (im Druck)
2010
Wedel T, Krammer HJ (2010) Anatomische und physiologische Grundlagen der gastrointestinalen Motilität. In Buchmann P, Degen L P (eds) Chronische Bauchbeschwerden. Verlag Hans Huber, Bern, Göttingen, Toronto
Wedel T, Böttner M (2010) Pathogenese der Divertikelkrankheit. In Kruis W (ed) Divertikelkrankheit. Verlag Uni-Med. Bremen, London, Boston
Wedel T, Pauli F (2010) Anatomische und chirurgische Grundlagen zur Netzrekonstruktion des Beckenbodens. Thieme Verlag.
2009
Wedel T, Krammer HJ (2009) Neuroanatomie und Neuropathologie.
In Jost W (ed) Neurokoloproktologie - Neurologie des Beckenbodens,
2. Auflage. Verlag Uni-Med. Bremen, London, Boston
Wedel T (2009) Ätiologie der chronischen Obstipation. In
Krammer HJ, Herold A (ed) Chronische Obstipation in der Praxis
und Klinik, Verlag Uni-Med. Bremen, London, Boston
2008
Wedel T (2008) Anatomy of the Colon, Rectum, Anus and
Pelvic Floor. In Herold A, Lehur PA, Matzel KE, O´Connell
PR (eds) European Manual of Medicine: Coloproctology. Springer.
Wedel T, Krammer HJ, Holschneider AM (2008) Electron microscopical
studies of Hirschsprung´s disease. In Holschneider AM, Puri
P (eds) Hirschsprung´s disease and allied disorders. 3.
edition. Springer.
2006
Krammer HJ, Schlieger F, Wedel T (2006) Intestinal comorbidity:
diverticular disease and chronic inflammatory bowel disease. In
Forbes, Jauch, Kruis, Wexner (eds) Diverticular Disease: Emerging
Evidence in a common condition. Springer, pp 69-75
Wedel T, Böttner M, Krammer HJ (2006) Pathogenesis of Diverticular
Disease: Enteric neuropathy. In Forbes, Jauch, Kruis, Wexner (eds)
Diverticular Disease: Emerging Evidence in a common condition.
Springer, pp 17-23
2005
Wedel T, Krammer HJ (2005) Neuroanatomie und Physiologie
des Kolons. In Jost W (ed) Neurologie des Beckenbodens - Neuroproktologie,
1. Auflage. Verlag Uni-Med. Bremen, London, Boston
2002
Wedel T, Krammer HJ (2002) Kolorektale Innervationsstörungen.
In Buchmann P (ed) Lehrbuch der Proktologie, 4. Auflage. Verlag
Hans Huber. Bern, Göttingen, Toronto, Seattle, pp 180-189
2001
Wedel T, Roblick UJ, Schiedeck THK, Schrader S, von Koschitzky
H, Bruch HP, Krammer HJ. (2001) Ist die Divertikelkrankheit mit
intestinalen Innervationsstörungen assoziiert? In Schumpelick
V, Kasperk R (eds) Divertikulitis - Eine Standortbestimmung. Springer.
Berlin, Heidelberg, New York, pp 38-43
Krammer HJ, Wedel T, Schäfer KH, Schiedeck THK, Roblick UJ,
Bruch HP (2001) Intrinsic innervation and innervational abnormalities
of the colorectum - from morphology to molecular genetics. In
Bruch HP, Frühmorgen P (eds) Non-Neoplastic Diseases of the
Anorectum - An Interdisciplinary Approach. Kluwer Academic Publishers.
Dordrecht, Boston, London, pp 26-37
2000
Krieger F, Wedel T, Meier-Ruge W, Singer MV, Krammer HJ (2000)
Immunohistochemical evaluation of the cholinergic, nitrergic and
peptidergic innervation of intestinal neuronal dysplasia (IND)
in children. The architectural heterogeneity of the enteric nervous
system in the forestomach of ruminants. In Krammer HJ, Singer
MV (eds) Neurogastroenterology - from the Basics to the Clinics.
Kluwer Academic Publishers. Dordrecht, Boston, London, pp 504-510
Schneider GBT, Wedel T, Dembowski C, Ehrenreich J, Singer MV,
Krammer HJ (2000) Three-dimensional architecture of the enteric
nervous system in homozygous endothelin-B-receptor (ETB) deficient
(spotting lethal) rats compared to patients with Hirschsprung´s
disease. In Krammer HJ, Singer MV (eds) Neurogastroenterology
- from the Basics to the Clinics. Kluwer Academic Publishers.
Dordrecht, Boston, London, pp 485-492
Wedel T, Roblick UJ, Schiedeck THK, Bruch HP, Krammer HJ (2000)
The enteric nervous system of the human colon demonstrated by
wholemount immunohistochemistry: normal structure and histopathlogy
in chronic intestinal motility disorders. In Krammer HJ, Singer
MV (eds) Neurogastroenterology - from the Basics to the Clinics.
Kluwer Academic Publishers. Dordrecht, Boston, London, pp 441-453
Teixeira AF, Wedel T, Kühnel W, Krammer HJ (2000) The architectural
heterogeneity of the enteric nervous system in the forestomach
of ruminants. In Krammer HJ, Singer MV (eds) Neurogastroenterology
- from the Basics to the Clinics. Kluwer Academic Publishers.
Dordrecht, Boston, London, pp 107-115
Leffler A, Wedel T, Busch LC (2000) Abnormalities of the enteric
nervous system in an animal model for Down´s Syndrome. In
Krammer HJ, Singer MV (eds) Neurogastroenterology - from the Basics
to the Clinics. Kluwer Academic Publishers. Dordrecht, Boston,
London, pp 496-503
Wedel T, Krammer HJ, Holschneider AM (2000) Electron microscopical
studies of Hirschsprung´s disease. In Holschneider AM, Puri
P (eds) Hirschsprung´s disease and allied disorders. Harwood
Academic Publishers. Amsterdam, pp 280-290
1999
Krammer HJ, Wedel T, Singer MV (1999) Kolorektale Innervation
und Innervationsstörungen - von der Morphologie zur Molekulargenetik.
In Kirchner T, Lembcke B, Kist M (eds) Ökosystem Darm VIII.
Springer. Berlin, pp 215-232
1998
Krammer HJ, Wedel T, Krieger F, Wessel L, Meier-Ruge W,
Singer MV (1998) Evaluation of the intrinsic nervous system in
human colonic biopsies by immunohistochemistry for neuronal and
glial proteins. In Holtmann G, Goebell H, Talley NJ (eds) Functional
and irritable bowel syndrom: Concepts and controversies. Kluwer
Academic Publishers. Dordrecht, Boston, Londen, pp 60-66
1995
Freund U, Krammer HJ, Sigge W, Wedel T, Kühnel W
(1995) Nerves and endocrine cells in the neomucosa. In Singer
MV, Ziegler R, Rohr G (eds) Gastrointestinal Tract and Endocrine
System. Kluwer Academic Publishers. Dordrecht, Boston, London,
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