| Scientific experience |
since 2008
Professor, Institute of Clinical Molecular Biology, CAU
2003-2008
Senior Research Scientist, Institute of Clinical Molecular Biology, CAU
2001-2003
Postdoctoral Research Fellow, Division of Human Genetics, University of the Witwatersrand, Johannesburg, South Africa
1991-1992
Postgraduate Research Fellow, Dept. of Biochemistry, University of Otago, Dunedin, New Zealand
1989-1991, 1993-1996
Human Geneticist, Institute of Clinical Genetics, Mainz, Germany
Important Functions:
Since 2011
Member of the Steering Group ‘Societal, Cultural and Environmental Change’, CAU
Since 2010
Scientific Coordinator of the new MSc study programme ‘Medical Life Sciences’, Medical Faculty, CAU
Since 2007
Founding member and member of the Executive Board of the DFG-Graduate School ‚Human Development in Landscapes‘, CAU
Projects
- Investigation of the molecular basis of human longevity and complex diseases using high-throughput technologies (projects funded by EU 7. FP, DFG, INTERREG 4A Syddanmark-Schleswig-K.E.R.N., Danone Foundation)
- Analysis of (human) genetic diversity in the present and the past, including ancient DNA research to address archaeological and anthropological questions, e.g. reconstruction of migrations, domestication of animals, effect of epidemics (projects funded by DFG-SPP 1400)
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| Selected publications |
2011
Huebbe P, Nebel A, Siegert S, Moehring J, Boesch-Saadatmandi C, Most E, Pallauf J, Egert S, Müller MJ, Schreiber S, Nöthlings U, Rimbach G: APOE epsilon 4 is associated with higher vitamin D levels in targeted replacement mice and humans. FASEB J, epub ahead of print.
2011
Kleindorp R, Flachsbart F, Puca AA, Malovini A, Schreiber S, Nebel A: Candidate gene study of FOXO1, FOXO4 and FOXO6 reveals no association with human longevity in Germans. Aging Cell, epub ahead of print.
2010
Caliebe A, Kleindorp R, Blanché H, Christiansen L, Puca AA, Rea IM, Slagboom E, Flachsbart F, Christensen K, Rimbach G, Schreiber S, Nebel A: No or only population-specific effect of PON1 on human longevity: A comprehensive meta-analysis. Ageing Res Rev 9: 238-244.
2009
Nebel A, Flachsbart F, Till A, Caliebe A, Blanché H, Arlt A, Häsler R, Jacobs G, Kleindorp R, Franke A, Shen B, Nikolaus S, Krawczak M, Rosenstiel P, Schreiber S: A functional EXO1 promoter variant is associated with prolonged life expectancy in centenarians. Mech Ageing Dev 130: 691-699.
2009
Flachsbart F, Caliebe A, Kleindorp R, Blanché H, von Eller-Eberstein H, Nikolaus S, Schreiber S, Nebel A: Association of FOXO3A variation with human longevity confirmed in German centenarians. Proc Natl Acad Sci USA 106: 2700-2705.
2008
Rosenstiel P, Derer S, Till A, Häsler R, Eberstein H, Bewig B, Nikolaus S, Nebel A, Schreiber S: Systematic expression profiling of innate immune genes defines a complex pattern of immunosenescence in peripheral and intestinal leukocytes. Genes Immun 9: 103-114.
2006
Flachsbart F, Croucher PJP, Nikolaus S, Hampe J, Cordes C, Schreiber S, Nebel A: Sirtuin 1 (SIRT1) sequence variation is not associated with exceptional human longevity. Exp Gerontol 41: 98-102.
2005
Nebel A, Croucher P, Stiegeler R, Nikolaus S, Krawczak M, Schreiber S: No association between microsomal triglyceride transfer protein (MTP) haplotype and longevity in humans. Proc Natl Acad Sci USA 102: 7906-7909.
2002
Nebel A, Landau-Tasseron E, Filon D, Oppenheim A, Faerman M: Genetic evidence for the expansion of Arabian tribes into the Southern Levant and North Africa. Am J Hum Genet 70: 1594-1596.
2001
Nebel A, Filon D, Brinkmann B, Majumder PP, Faerman M, Oppenheim A: The Y chromosome pool of Jews as part of the genetic landscape of the Middle East. Am J Hum Genet 69: 1095-1112.
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