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 1990

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2011

Literatur 2011 (Download als PDF-Dokument)

2010

Literatur 2010 (Download als PDF-Dokument)

2009

Literatur 2009 (Download als PDF-Dokument)

2008

Literatur 2008 (Download als PDF-Dokument)

2007

Literatur 2007 (Download als PDF-Dokument)

2006

Literatur 2006 (Download als PDF-Dokument)

2005

Beck C, Humpe A, Harder S, Schmid M, Horst HA:
Myelodysplastic syndrome of donor origin subsequent to successful treatment of myeloid/NK-cell precursor leukaemia with allogeneic PBSCT: two very rare conditions in one patient.
Ann Hematol 84:616-618 (2005)

Birgander PL, Bug S, Kasrayan A, Dahlroth S, Westman M, Gordon E, Sjöberg BM:
Nucleotide-dependent formation of catalytically competent dimers from engineered monomeric ribonucleotide reductase protein R1.
J Biol Chem 280:4997-5003 (2005)

Frohling S, Schlenk RF, Krauter J, Thiede C, Ehninger G, Haase D, Harder L, Kreitmeier S, Scholl C, Caligiuri MA, Bloomfield CD, Dohner H, Dohner K:
Acute myeloid leukemia with deletion 9q within a noncomplex karyotype is associated with CEBPA loss-of-function mutations.
Genes Chromosomes Cancer 42:427-432 (2005)

Fu K, Weisenburger DD, Greiner TC, Dave S, Wright G, Rosenwald A, Chiorazzi M, Iqbal J, Gesk S, Siebert R, de Jong D, Jaffe ES, Wilson WH, Delabie J, Ott G, Dave BJ, Sanger WG, Smith LM, Braziel RM, Müller-Hermelink HK, Campo E, Gascoyne RD, Staudt LM, Chan WC:
Cyclin D1-negative mantle cell lymphoma: a clinicopathological study based on gene expression profiling.
Blood 106:4315-4321 (2005)

Frühwald MC, Hasselblatt M, Wirth S, Köhler G, Schneppenheim R, Martin-Subero JI, Siebert R, Kordes U, Jürgens H, Vormoor J:
Non-linkage of familial rhabdoid tumors to SMARCB1 implies a second locus for the rhabdoid tumor predisposition syndrome.
Pediatric Blood and Cancer (in press) (2005)

Gesk S, Gascoyne RD, Schnitzer B, Bakshi N, Janssen D, Klapper W, Martin-Subero JI, Parwaresch R, Siebert R:
ALK-positive diffuse large B-cell lymphoma with ALK-Clathrin fusion belongs to the spectrum of pediatric lymphomas.
Leukemia 19:1839-1840 (2005)

Karpas A, Harder L, Czepulkowski B, Bloxham D, Dremucheva A, Siebert R:
Studies of four new human myeloma cell lines.
Leukemia Lymphoma 46:101-112 (2005)

Marafioti T, Pozzobon M, Hansmann ML, Ventura R, Pileri SA, Roberton H, Gesk S, Gaulard P, Barth TFE, Du MQ, Leoncini L, Möller P, Natkunam, Siebert R, Mason DY:
The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomas.
Br J Haematol 128:333-342 (2005)

Marafioti T, Pozzobon M, Hansmann ML, Gaulard P, Barth TF, Copie-Bergman C, Roberton H, Ventura R, Martin-Subero JI, Gascoyne RD, Pileri SA, Siebert R, Hsi ED, Natkunam Y, Moller P, Mason DY:
Expression pattern of intracellular leukocyte-associated proteins in primary mediastinal B cell lymphoma.
Leukemia 19:856-861 (2005)

Martín-Subero JI, Odero MD, Hernandez R, Cigudosa JC, Agirre X, Saez B, Sanz-García E, Ardanaz MT, Novo FJ, Gascoyne RD, Calasanz MJ, Siebert R:.
Amplification of IGH/MYC fusion in clinically aggressive IGH/BCL2-positive germinal center B-cell lymphomas.
Genes Chromosomes Cancer 43:414-423 (2005)

Mestre C, Rubio-Moscardo F, Siebert R, Rosenwald A, Climent J, Staudt LM, Dyer MJS, Pinkel D, Martinez-Climent JA:
Homozygous deletion of SOCS1 in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays.
Leukemia 19:1082-1084 (2005)

Metzke-Heidemann S, Kirsch E, Jordan S, Crohns C, Siebert R, Maaß N, Grote W, Gerber WD, Schreer I, Schmutzler R, Arnold N, Jonat W:
Beratung, genetische Diagnostik und Betreuung von Familien mit Veranlagung für Mamma-/Ovarialkarzinome.
Schleswig-Holsteinisches Ärzteblatt 9:51-56 (2005)

Partsch CJ, Siebert R, Caliebe A, Gosch A, Wessel A, Pankau R:
Sigmoid diverticulitis in patients with Williams-Beuren syndrome: Relatively high prevalence and high complication rate in young adults with the syndrome.
Am J Med Genet 137:52-54 (2005)

Pott C, Schrader C, Brüggemann M, Ritgen M, Harder L, Raff T, Tiemann M, Dreger P, Kneba M:
Blastoid variant of mantle cell lymphoma: late progression from classical mantle cell lymphoma and quantitation of minimal residual disease.
Eur J Haematol 74:353-358 (2005)

Pott C, Schrader C, Gesk S, Harder L, Tiemann M, Raff T, Brüggemann M, Ritgen M, Gahn B, Unterhalt M, Dreyling M, Hiddemann W, Siebert R, Dreger P, Kneba M:
Quantitative assessment of molecular remission following high-dose therapy with autologous stem cell transplantation predicts long term remission in mantle cell lymphoma.
Blood (in press) (2005)

Przybylski GK, Dik WA, Wanzeck J, Grabarczyk P, Majunke S, Martin-Subero JI, Siebert R, Dölken G, Ludwig WD, Verhaaf B, van Dongen JJM, Schmidt CA, Langerak AW:
Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in expression of BCL11B-TRDC fusion transcripts and is associated with absence of wild-type BCL11B transcripts in T-ALL.
Leukemia 19:201-208 (2005).

Renne C, Martin-Subero JI, Hansmann ML, Siebert R:
Translocations affecting the IGH locus in nodular lymphocyte predominant Hodgkin´s lymphoma recurrently involve the BCL6 gene.
J Mol Diagn 7:352-356 (2005).

Rubio-Moscardo F, Climent J, Siebert R, Piris MA, Martin-Subero JI, Nielander I, Garcia-Conde J, Dyer MJ, Terol MJ, Pinkel D, Martinez-Climent JA:
Mantle cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome.
Blood 106:3214-3222 (2005)

Trauzold A, Roder C, Sipos B, Karsten K, Arlt A, Martin-Subero JI, Siegmund D, Muerkoster S, Pagerols Raluy L, Siebert R, Wajant H, Kalthoff H:
CD95 and TRAF2 promote invasiveness of pancreatic cancer cells.
FASEB J 19:620-622 (2005).

Ventura RA, Martin-Subero JI, Jones M, McParland J, Gesk S, Mason DY, Siebert R:
FISH analysis for the detection of lymphoma-associated chromosomal abnormalities in routine paraffin-embedded tissue.
J Mol Diag (in press) (2005)

Weise JB, Plendl H, Gieseler F, Preuss S, Maune S:
Acute airway obstruction in acquired hemophilia A.
HNO 53:462-466 (2005)

Ye H, Gong L, Liu H, Hamoudi RA, Shirali S, Ho L, Chott A, Streubel B, Siebert R, Gesk S, Martin-Subero JI, Radford JA, Banerjee S, Nicholson AG, Ranaldi R, Remstein ED, Gao Z, Zheng J, Isaacson PG, Dogan A, Du MQ:
MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression.
J Pathol 205:293-301 (2005).

zurück  zurück

2004

Hallermann C, Kaune KM, Siebert R, Vermeer MH, Tensen CP, Willemze R, Gunawan B, Bertsch HP, Neumann C:
Chromosomal aberration patterns differ in subtypes of primary cutaneous B-cell lymphomas.
J Invest Dermatol 122: 1495-1502 (2004)

Metzke-Heidemann S, Kuhling-von Kaisenberg H, Caliebe A, Janssen D, Jonat W, Grote W, von Kaisenberg CS
Phenotypical Variation in Cousins With the Identical Partial Trisomy 9 (pter-q22.2) and 7 (q35-qter) at 16 and 23 Weeks Gestation
Am J Med Genet 126A:197-203 (2004)

Höglund M, Sehn L, Connors JM, Gascoyne RD, Siebert R, Säll T, Mitelman F, Horsman DE:
Identification of cytogenetic subgroups and karyotypic pathways of clonal evolution in follicular lymphomas.
Genes Chrom Cancer 39:195-204 (2004)

Krugmann J, Tzankov A, Dirnhofer S, Fend F, Greil R, Siebert R, Erdel M:
Unfavourable prognosis of patients with trisomy 18q21 detected by fluorescence in situ hybridization in t(11;18)-negative surgically resected gastrointestinal B-cell lymphomas.
J Clin Pathol 57: 360-364 (2004)

Krugmann J, Tzankov A, Fiegl M, Dirnhofer S, Siebert R, Erdel M:
Burkitt`s lymphoma of the stomach: a case report with molecular cytogenetic analysis.
Leuk Lymphoma 45: 1055-1059 (2004)

Saez B, Martin-Subero JI, Guillen-Grima F, Odero MD, Prosper F, Cigudosa JC, Harder L, Calasanz MJ, Siebert R:
Chromosomal abnormalities clustering in multiple myeloma reveals cytogenetic subgroups with nonrandom acquisition of chromosomal changes.
Leukemia [Epub ahead of print] (2004)

Sarafidou T, Kahl C, Martinez-Garay I, Mangelsdorf M, Gesk S, Baker E, Kokkinaki M, Talley P, Maltby EL, French L, Harder L, Hinzmann B, Nobile C, Richkind K, Finnis M, European Collaborative Consortium for the study of ADLTE, Deloukas P, Sutherland GR, Kutche K, Moschonas NK, Siebert R, Gecz J:
Folate-sensitive fragile site FRA10A is due to an expansion of a CGG-repeat in a novel gene FRA10AC1, encoding a nuclear protein.
Genomics 84: 69-81 (2004)

Kluwe L, Siebert R, Gesk S, Friedrich RE, Tinschert S, Kehrer-Sawatzki H, Mautner VF:
Screening 500 unselected neurofibromatosis 1 patients for deletions of the NF1 gene.
Hum Mutat. 23:111-16 (2004)

Ventura RA, Martin-Subero JI, Knippschild U, Gascoyne RD, Delsol G, Mason DY, Siebert R:
Centrosome abnormalities in ALK-positive anaplastic large cell lymphoma.
Leukemia 18:1910-1911 (2004)

Subklewe M, Nagy M, Schoch C, Jenisch S, Siebert R, Gesk S, Neuhaus P, Dörken B:
Extramedullary manifestation of a donor-derived acute myeloid leukemia in a liver transplant patient.
Leukemia 18:2050-2053 (2004)

Streubel B, Simonitsch-Klupp I, Müllauer L, Lamprecht A, Huber A, Siebert R, Stolte M, Trautinger F, Lukas J, Püspök A, Formanek M, Assanasen T, Müller-Hermelink HK, Cerroni L, Raderer M, Chott A:
Variable frequencies of MALT lymphoma-associated genetic aberrations in MALT lymphomas of different sites.
Leukemia 18:1722-1726 (2004)

Sonoki T, Willis TG, Oscier DG, Karran EL, Siebert R, Dyer MJS:
Rapid amplification of immunoglobulin breakpoints using long distance inverse PCR (LDI-PCR).
Leukemia 18:2026-2031 (2004)

Klein F, Feldhahn N, Harder L, Wang H, Wartenberg M, Hofmann WK, Wernet P, Siebert R, Müschen M:
The BCR-ABL1 kinase bypasses selection for the expression of a pre-B cell receptor in pre-B acute lymphoblastic leukemia cells.
J Exp Med 199:673-685 (2004)

Jandrig B, Seitz S, Hinzmann B, Arnold W, Micheel B, Koelble K, Siebert R, Schwartz A, Ruecker K, Schlag PM, Scherneck S, Rosenthal A:
ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2.
Oncogene 23:9295-9302 (2004).

Hallermann C, Kaune KM, Gesk S, Martin-Subero JI, Gunawan B, Griesinger F, Vermeer MH, Willemze R, Siebert R, Neumann C:
Molecular cytogenetic analysis of chromosomal breakpoints in the IGH, MYC, BCL6 and MALT1 gene loci in primary cutaneous B-cell lymphomas.
J Invest Dermatol 123: 213-219 (2004)

Deppe SF, Wachsmuth U, Abel B, Bittererova M, Grebenshchikov SY, Siebert R, Schinke R:
Resonance spectrum and dissociation dynamics of ozone in the 3B2 electronically excited state: experiment and theory.
J Chem Phys 121:5191-5200 (2004)

Deloukas P, Earthrowl ME, Grafham DV, Rubenfield M, French L, Steward C, Sims SK, Jones MC, Searle S, Scott C, Howe K, Hunt SE, Andrews TD, Gilbert JGR, Swarbreck D, Ashurst JL, Taylor A, Battles J, Bird CP, Ainscough R, Almeida JP, Ashwell RIS, Ambrose KD, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Bates K, Beasley H, Bray-Allen S, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Cahill P, Camire D, Carter NP, Chapmann JC, Clark SY, Clarke G, Clee CM, Clegg S, Corby N, Coulson A, Dhami P, Dutta I, Dunn M, Faulkner L, Frankish A, Frankland JA, Garner P, Garnett J, Gribble S, Griffiths C, Grocock R, Gustafson E, Hammond S, Harley JL, Hart E, Heath PD, Ho TP, Hopkins B, Horne J, Howden PJ, Huckle E, Hynds C, Johnson C, Johnson D, Kana A, Kay M, Kimberley AM, Kershaw JK, Kokkinaki M, Laird GK, Lawlor S, Lee HM, Leongamornlert DA, Laird G, Lloyd C, Lloyd DM, Loveland J, Lovell J, McLaren S, McLay KE, McMurray A, Mashreghi-Mohammadi M, Matthews L, Milne S, Nickerson T, Nguyen M, Overton-Larty E, Palmer SA, Pearce AV, Peck AI, Pelan S, Phillimore B, Porter K, Rice CM, Rogosin A, Ross MT, Sarafidou T, Sehra HK, Shownkeen R, Shuce CD, Smith M, Standring L, Sycamore N, Tester J, Thorpe A, Torcasso W, Tracey A, Tromans A, Tsolas J, Wall M, Walsh J, Wang H, Weinstock K, West AP, Willey DL, Whitehead SL, Wilming L, Wray PW, Young L, Chen Y, Lovering RC, Moschonas NK, Siebert R, Fechtel K, Bentley D, Durbin R, Hubbard T, Doucette-Stamm L, Beck S, Smith DR, Rogers J:
The DNA sequence and comparative analysis of human chromosome 10.
Nature 429: 375-381 (2004)

Barth TF, Müller S, Pawlita M, Siebert R, Rother JU, Mechtersheimer G, Kitinya J, Bentz M, Möller P:
Homogeneous immunophenotype and paucity of secondary genomic aberrations are distinctive features of endemic but not of sporadic Burkitt‘s lymphoma and diffuse large B-cell lymphoma with MYC rearrangement.
J Pathol 203: 940-945 (2004)

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2003

Martin-Subero JI,, Gesk S,,Harder L, Grote W, Siebert R
Interphase cytogenetics of hematological neoplasms under the perspective of the novel WHO classification.
Anticancer Res.23(2A):1139-48 (2003)

Assaf C, Hummel M, Dippel E, Schwartz S, Geilen CC, Harder L, Siebert R, Steinhoff M, Klemke CD, Thiel E, Goerdt S, Stein H, Orfanos CE:
Common clonal T-cell origin in a patient with T-prolymphocytic leukaemia and associated cutaneous T-cell lymphomas.
Br J Haematol 120:488-91 (2003)

Barth TFE, Martin-Subero JI, Joos S, Menz CK, Hasel C, Mechtersheimer G, Parwaresch RM, Lichter P, Siebert R, Möller P:
Gains of 2p involving the REL locus correlate with nuclear c-Rel protein accumulation in neoplastic cells of classical Hodgkin's lymphoma.
Blood 101:3681-86 (2003)

Besleaga R, Montesinos-Rongen M, Perez-Tur J, Siebert R, Deckert M:
Expression of the LGl1 product in astrocytic gliomas: downregulation with malignant progression.
Virchows Arch. 443:561-64 (2003)

Bevan S, Edwards SM, Arderns Jones A, Dowe A, Southgate C, The CRC/BPG UK Familial Prostate Cancer Study Collaborators, Dearnaley D, Easton DF, Houlston RS, Eeles RA:
Germline mutations in fumarate hydratade (FH) do not predispose to prostate cancer.
Prostate Cancer and Prostatic Disease 6:12-14 (2003)

Edwards SM, Kote-Jarai Z, Meitz J, Hamoudi R, Hope Q, Osin P, Jackson R, Southgate C, Singh R, Falconer A, Dearnaley DP, Ardern-Jones A, Murkin A, Dowe A, Kelly J, Williams S, Oram R, Stevens M, Teare DM, Ponder BAJ, Gayther SA, The CRC/BPG UK Familial Prostate Cancer Study Collaborators, British Association of Urological Surgeons Section of Oncology, Easton DF, Eeles RA:
Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene
Am J Hum Genet 72:1-12 (2003)

Gascoyne RD, Laurence Lamant L, Martin-Subero JI, Lestou VS, Harris NL, Müller-Hermelink HK, Seymour JF, Horsman DE, Auvigne I, Espinos E, Siebert R, Delsol G:
ALK-positive diffuse large B-cell lymphoma is associated with Clathrin-ALK rearrangements: report of six cases.
Blood 102:2568-73 (2003)

Gesk S, Martin-Subero JI, Harder L, Luhmann B, Schlegelberger B, Calasanz MJ, Grote W, Siebert R:
Molecular cytogenetic detection of chromosomal breakpoints in T-cell receptor loci.
Leukemia 17:738-45 (2003)

Harder L, Gesk S, Martin-Subero JI, Merz H, Hochhaus A, Maaß E, Feller A, Grote W, Siebert R, Fetscher S:
Cytogenetic and molecular characterization of simultaneous chronic and acute myeloid leukemia.
Cancer Genet Cytogenet 142:80-82 (2003)

Horsmann D, Okamoto I, LudkovskiO, Le N, Harder L, Gesk S, Siebert R, Chhanabhai M, Sehn L, Connors J, Gascoyne R:
Follicular lymphoma lacking the t(14;18)(q32;q21): identification of two diseases.
Br J Haematol 120:424-433 (2003)

Jepsen S, Eberhard J, Fricke D, Hedderich J, Siebert R, Acil Y:
Interleukin-1 gene polymorphisms and experimental gingivitis.
J Clin Periodontology 30:102-06 (2003)

Joos S, Granzow M, Holtgreve-Grez H, Siebert R, Harder L, Martin-Subero JI, Wolf J, Barth TFE, Lichter P, Jauch A:
Hodgkin lymphoma cell lines are characterized by frequent aberrations on chromosome 2p and 9p including REL and JAK2.
Int J Cancer 103:489-95 (2003)

Lossos IS, Akasaka T, Martinez-Climent JA, Siebert R, Levy R:
The BCL6 gene in B-cell lymphomas with 3q27 translocations is expressed mainly from the rearranged allele irrespective of the partner gene.
Leukemia 17:1390-97 (2003)

Martinez-Climent JA, Sanchez-Izquierdo D, Sarsotti E, Blesa D, Benet I, Climent J, Vizcarra E, Marugan I, Terol MJ, Sole F, Cigudosa JC, Siebert R, Dyer MJ, Garcia-Conde J:
Genomic abnormalities acquired in the blastic transformation of splenic marginal zone B cell lymphoma.
Leuk Lymphoma 44:459-464 (2003)

Martin-Subero JI, Knippschild U, Harder L, Barth TF, Riemke J, Grohmann S, Gesk S, Hoppner J, Moller P, Parwaresch RM, Siebert R:
Segmental chromosomal aberrations and centrosome amplifications: pathogenetic mechanisms in Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma?
Leukemia 17:2214-9 (2003)

Michelucci R, Poza JJ, Sofia V, de Feo MR, Binelli S, Bisulli F, Scudellaro E, Simionati B, Zimbello R, d`Orsi G, Passarelli D, Avoni P, Avanzini G, Tinuper P, Biondi R, Valle G, Mautner VF, Stephani U, Tassinari CA, Moschonas NK, Siebert R, Lopez de Munain A, Perez-Tur J, Nobile C:
Autosomal dominant lateral temporal epilepsy: the clinical spectrum, new epitemp in mutations and genetic heterogeneity in seven european families.
Epilepsia 44:1289-1297 (2003)

Miller K, Pabst B, Ritter H, Nürnberg P, Siebert R, Schmidtke J, Arslan-Kirchner M:
Chromosome 18 replaced by two ring chromosomes of chromosome 18 origin.
Hum Genet 112:343-47 (2003)

Montesinos-Rongen M, Akasaka T, Zühlke-Jenisch R, Schaller C, van Roost D, Wiestler OD, Siebert R, Deckert M:
Molecular characterization of BCL6 breakpoints in primary diffuse large B-cell lymphomas of the central nervous system identifies GAPD as novel translocation partner.
Brain Pathol 13:534-38 (2003)

Sanchez-Izquierdo D, Buchonnet G, Siebert R, Gascoyne RD, Climent J, Karran EL, Marin M, Blesa D, Horsman D, Rosenwald A, Staudt LM, Albertson DG, Du MQ, Ye H, Marynen P, Garcia-Conde J, Pinkel D, Dyer MJS, Martinez-Climent JA:
MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma.
Blood 101:4539-46 (2003)

Steinemann D, Gesk S, Zhang Y, Harder L, Pilarsky C, Hinzmann B, Martin-Subero JI, Calasanz MJ, Mungall A, Rosenthal A, Siebert R, Schlegelberger B:
Identification of candidate tumor suppressor genes in 6q27 by combined deletion mapping and electronic expression profiling in lymphoid neoplasms.
Genes Chrom Cancer 37:421-426 (2003)

Weng L, Gesk S, Martin-Subero JI, Harder L, Schlegelberger B, Grote W, Dyer MJS, Siebert R:
Interphase cytogenetic characterization of aberrations in the long arm of chromosome 1 in B-cell lymphoid malignancies.
Cancer Genet Cytogenet 144:83-84 (2003)

Wlodarska I, Nooyen P, Maes B, Martin-Subero JI, Siebert R, Pauwels P, De Wolf-Peeters C, Hagemeijer A:
Rearrangement of BCL6 is frequent in lymphocyte predominance Hodgkin´s lymphoma and absent in classical Hodgkin´s lymphoma.
Blood 101:706-10 (2003)

Ye H, Liul H, Attygallel A, Wotherspoon AC, Nicholson AG, Charlotte F, Leblond V, Speight P, Goodlad J, Lavergne-Slove A, Martin-Subero JI, Siebert R, Dogan A, Isaacson PG, Du MQ:
Variable frequencies of t(11;18) (q21;q21) in MALT lymphomas of different sites: Significant association with CagA strains of H. pylori in gastric MALT lymphoma.
Blood 102:1012-18 (2003)

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2002

Barth TFE, Bentz M, Leithauser F, Stilgenbauer S, Siebert R, Schlotter M, Schlenk RF, Döhner H, Möller P:
Pathogenic complexity of gastric B-cell-lymphoma.
Blood 100:1095-1097 (2002)

Dunsche A, Açil Y, Dommisch H, Siebert R, Schröder JM, Jepsen S:
The novel human beta-defensin-3 is widely expressed in oral tissues.
Eur J Oral Sci 109:121-124 (2002)

Flesch B, Doose S, Siebert R, Ntambi E, Neppert J:
FCGR3 variants and expression of the human neutrophil antigens HNA-1a, HNA-1b and HNA-1c in the population of Northern Germany and Uganda.
Transfusion 42:469-475 (2002)

Frenzel H, Hampe J, Huse K, Mascheretti SM, Croucher PJP, Lynch NJ, Siebert R, Platzer M, Schreiber S:
Mutation detection and physical mapping of the CD11 gene cluster in association with inflammatory bowel disease.
Immunogenetics 53:835-842 (2002)

Joos S, Menz CK, Wrobel G, Siebert R, Gesk S, Ohl S, Mechtersheimer G, Trümper L, Möller P, Lichter P, Barth TFE:
Classical Hodgkin's lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2.
Blood 99:1381-87. (2002)

Kote-Jarai Z, Durocher F, Edwards SM, Hamoudi R, Jackson RA, Ardern-Jones A, Murkin A, Dearnaley DP, Kirby R, Houlston R, Easton DF, Eeles R, The CRC/BPG UK Familial Prostate Cancer Study Collaborators:
Association between the GCG polymorphism of the selenium dependent GPX1 gene and the risk of young onset prostate cancer.
Prostate Cancer P D 5:189-192 (2002)

Küppers R, Sonoki T, Satterwhite E, Gesk S, Harder L, Oscier DG, Tucker PW, Dyer MJS, Siebert
Lack of somatic hypermutation of IG V(H) genes in lymphoid malignancies with t(2;14)(p13;q32) translocation involving the BCL11A gene.
Leukemia 16:937-939 (2002)

Martin-Subero JI, Chudoba I, Harder L, Gesk S, Novo FJ, Calasanz MJ, Grote W, Siebert R:
Multicolor-Fluorescence immunophenotyping and interphase cytogenetics as a tool for the investigation of neoplasms: expanding the possibilities of combined morphologic, immunophenotypic and genetic single cell analyses.
Am J Pathol 161:413-420 (2002)

Martin-Subero JI, Gesk S, Harder L, Sonoki T, Tucker PW, Schlegelberger B, Grote W, Novo FJ, Calasanz MJ, Hansmann ML, Dyer MJS, Siebert R:
Recurrent involvement of the REL and BCL11A loci in classical Hodgkin’s lymphoma.
Blood 99:1474-1477 (2002)

Martin-Subero JI, Harder L, Gesk S, Schlegelberger B, Grote W, Martinez-Climent JA, Dyer MJS, Novo FJ, Calasanz MJ, Siebert R:
Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci.
Int J Cancer 98: 470-474 (2002)

McCarron SL, Edwards S, Evans PR, Dowe A, Arden-Jones A, Southgate C, Dearnaley D, The CRC/BPG UK Familial Prostate Cancer Study Collaborators, Easton DF, Eeles R, Howell WM:
Influence of cytokine polymorphisms on susceptibility to and/or prognosis in prostate cancer.
Br J Cancer 86 (Suppl.):S24 (2002)

McCarron SL, Edwards S, Evans PR, Gibss R, Dearnaley DP, Dowe A, Southgate C, The CRC/BPG UK Familial Prostate Cancer Study Collaborators, Easton DF, Eeles RA, Howell WM:
Influence of cytokine gene polymorphisms on the development of prostate cancer.
Cancer Res 62:3369-3372 (2002)

Meitz JC, Edwards SM, Easton DF, Murkin A, Ardern-Jones A, Jackson RA, Williams S, Dearnaley DP, Stratton MR, Houlston RS, The CRC/BPG UK Familial Prostate Cancer Study Collaborators, Eeles RA:
HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease.
Br J Cancer 87:905-908 (2002)

Merz H, Lange K, Gaiser T, Müller A, Kapp U, Bittner C, Harder S, Siebert R, Bentz M, Binder T, Diehl V Feller AC:
Characterization of a novel human anaplastic large cell lymphoma cell line tumorigenic in SCID mice.
Leukemia Lymphoma 43:165-172 (2002)

Montesinos-Rongen Manuel, Zühlke-Jenisch R, Gesk S, Martin-Subero JI, Schaller C, Van Roost D, Wiestler OD, Deckert M, Siebert R:
Interphase cytogenetic analysis of lymphoma-associated chromosomal breakpoints in primary diffuse large B-cell lymphomas of the central nervous system.
J Neuropath Exp Neur 61:926-933 (2002)

Morante-Redolat JM, Gorostidi-Pagola A, Piquer-Sirerol S, Saenz A, Poza JJ, Galan J, Gesk S, Sarafidou T, Mautner VF, Binelli S, Staub E, Hinzmann B, French L, Prud'homme JF, Passarelli D, Scannapieco P, Tassinari CA, Avanzini G, Marti-Masso JF, Kluwe L, Deloukas P, Moschonas NK, Michelucci R, Siebert R, Nobile C, Perez-Tur J, Lopez de Munain A:
Mutations in the LGI1/Epitempin gene on 10q24 cause autosomal dominant lateral temporal epilepsy.
Hum Mol Genet 11: 1119-1128 (2002)

Morava E, Karteszi J, Weisenbach J, Caliebe A, Mundlos S, Mehes K:
Cleidocranial dysplasia with decreased bone density and biochemical findings of hypophosphatasia.
Eur J Pediatr 161:619-622 (2002)

Nobile C, Hinzmann B, Scannapieco P, Siebert R, Zimbello R, Perez-Tur J, Sarafidou T, Moschonas NK, French L, Deloukas P, Ciccodicola A, Gesk S, Poza JJ, Lo Nigro C, Seri M, Schlegelberger B, Rosenthal A, Valle G, Lopez de Munain A, Tassinari CA, Michelucci R:
Identification and characterization of a novel human brain-specific gene, homologous to S. scrofa tmp83.5, in the chromosome 10q24 critical region for temporal lobe epilepsy and spastic paraplegia.
Gene 282:87-94 (2002)

Partsch CJ, Japing I, Siebert R, Gosch A, Wessel A, Sippell WG, Pankau R:
Central precocious puberty in girls with Williams syndrome.
J Pediatrics 141:441-444 (2002)

Plendl H, Caliebe A, Grote W:
Molekulare Varianten des Fibrinogen.
Haemostaseologie 22:36-41 (2002)

Staub E, Pérez-Tur J, Siebert R, Nobile C, Moschonas NK, Deloukas P, Hinzmann B:
The novel EPTP repeat defines a superfamily of proteins with implications in epileptic disorders.
Trends Biochem Sci 27:441-444 (2002)

Viardot A, Möller P, Högel J, Werner K, Mechtersheimer G, Ho AD, Ott G, Barth TFE, Siebert R, Gesk S, Schlegelberger B, Döhner H, Bentz M:
Clinicopathological correlations of genomic gains and losses in follicular lymphoma.
J Clin Oncol 20:4523-4530 (2002)

Vockerodt M, Belge G, Kube D, Irsch J, Siebert R, Tesch H, Diehl V, Wolf J, Bullerdiek J, Staratschek-Jox A:
An unbalanced translocation involving chromosome 14 is the probable cause for loss of potentially functional rearranged immunoglobulin heavy chain genes in the EBV-positive Hodgkin´s lymphoma-derived cell line L591.
Br J Haematol 119:640-646 (2002)

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2001

Barth TFE, Bentz M, Leithäuser F, Stilgenbauer S, Siebert R, Schlotter M, Schlenk RF, Döhner H, Möller P:
Molecular cytogenetic comparison of mucosa-associated marginal zone B-cell lymphoma and large B-cell lymphoma arising in the gastro-intestinal tract.
Gene Chromosome Cancer 31:316-325. (2001)

Dunsche A, Acil Y, Siebert R, Harder J, Schröder JM, Jepsen S:
Expression profile of human defensins and antimicrobial proteins in oral tissues.
J Oral Pathol Med 30:154-158. (2001)

Frenzel H, Hampe J, Huse K, Mascheretti SM, Croucher PJP, Lynch NJ, Siebert R, Platzer M, Schreiber
Mutation detection and physical mapping of the CD11 gene cluster in association with inflammatory bowel disease.
submitted

Kahl C, Gesk S, Harder L, Harbott J, French L, Deloukas P, Grote W, Schlegelberger B, Siebert R:
Detection of translocations involving the HOX11/TCL3-Locus in 10q24 by interphase-FISH.
Cancer Genet Cytogenet 129:80-84. (2001)

Martín-Subero JI, Harder L, Gesk S, Schoch R, Novo FJ, Grote W, Calasanz MJ, Schlegelberger B, Siebert R:
Amplification of ERBB2, RARa and TOP2A genes in a myelodysplastic syndrome transforming to acute myeloid leukemia.
Cancer Genet Cytogenet 127:174-6. (2001)

The International Human Genome Mapping Consortium: McPherson JD, Marra M, Hillier L, Waterston RH, Chinwalla A, Wallis J, Sekhon M, Wylie K, Mardis ER, Wilson RK, Fulton R, Kucaba TA, Wagner-McPherson C, Barbazuk WB, Gregory SG, Humphray SJ, French L, Evans RS, Bethel G, Whittaker A, Holden JL, McCann OT, Dunham A, Soderlund C, Scott CE, Bentley DR, Schuler G, Chen HC, Jang W, Green ED, Idol JR, Braden Maduro VV, Montgomery KT, Lee E, Miller A, Emerling S, Kucherlapati R, Gibbs R, Scherer S, Gorrell JH, Sodergren E, Clerc-Blankenburg K, Tabor P, Naylor S, Garcia D, de Jong PJ, Catanese JJ, Nowak N, Osoegawa K, Qin S, Rowen L, Madan A, Dors M, Hood L, Trask B, Friedman C, Massa H, Cheung VG, Kirsch IR, Reid T, Yonescu R, Weissenbach J, Bruls T, Heilig R, Branscomb E, Olsen A, Doggett N, Cheng JF, Hawkins T, Myers RM, Shang J, Ramirez L, Schmutz J, Velasquez O, Dixon K, Stone NE, Cox DR, Haussler D, Kent WJ, Furey T, Rogic S, Kennedy S, Jones S, Rosenthal A, Wen G, Schilhabel M, Gloeckner G, Nyakatura G, Siebert R, Schlegelberger B, Korenberg J, Chen XN, Fujiama A, Hattori M, Toyoda A, Yada T, Park HS, Sakaki Y, Shimizu N, Asakawa S, Kawasaki K, Sasaki T, Shintani A, Shimizu A, Shibuya K, Kudoh J, Minoshima S, Ramser J, Seranski P, Hoff C, Poustka A, Reinhardt R, Lehrach H:
A physical map of the human genome.
Nature 409:934-941. (2001)

Metzke-Heidemann S, Harder L, Gesk S, Schoch R, Jenisch S, Grote W, Siebert R, Schlegelberger B:
Integration of amplified BCR/ABL fusion genes into the short arm of chromosome 17 as a novel mechanism of disease progression in chronic myeloid leukemia.
Gene Chromosome Cancer 31:10-14. (2001)

Pankau R, Siebert R, Kautza M, Schneppenheim R, Gosch A, Wessel A, Partsch CJ:
Familial Williams-Beuren Syndrome showing varying clinical expression.
Am J Med Genet 98:324-329. (2001)

Plendl HJ, Siebert R, Steinemann D, Grote W:
High frequency of the N34S mutation in the SPINK1 gene in chronic pancreatitis detected by a new PCR-RFLP assay.
Am J Med Genet 100:252-253. (2001)

Sanchez-Izquierdo D, Siebert R, Harder L, Marugan I, Gozzetti A, Price HP, Gesk S, Hernandez-Rivas JM, Benet I, Solé F, Sonoki T, Le Beau MM, Schlegelberger B, Dyer MJS, Garcia-Conde J, Martinez-Climent JA:
Detection of translocations affecting the BCL6 locus in B-cell non-Hodgkin's lymphoma by interphase fluorescence in situ hybridization.
Leukemia 15:1475-1484. (2001)

Steinemann D, Siebert R, Harder S, Martin-Subero I, Kettwig G, Hinzmann B, Gesk S, Tiemann, M, Merz H, Rosenthal A, Grote W, Morris SW, Schlegelberger B:
Frequent allelic loss of the BCL10 gene in lymphomas with the t(11;14)(q13;q32).
Leukemia 15:474-477. (2001)

Stumm M, von Ruskowsky A, Siebert R, Harder S, Varon R, Wieacker P, Schlegelberger B:
No evidence for deletions of the NBS1 gene in lymphomas.
Cancer Genet Cytogenet 126:60-62. (2001)

Viardot A, Martín-Subero JI, Siebert R, Harder S, Gesk S, Bentz M, Schlegelberger B:
Detection of secondary genetic aberrations in follicle center cell derived lymphomas: assessment of the reliability of comparative genomic hybridization and standard chromosome analysis.
Leukemia 15:177-183. (2001)

Weidmann E, Boehrer S, Chow KU, Engels K, Harder L, Hinz T, Janssen O, Kriener S, Rummel MJ, Siebert R, Kabelitz D, Hansmann ML, Hoelzer D, Mitrou PS for the ‚Study Group Peripheral T- and NK-cell neoplasias':
Treatment of aggressive or progressing indolent peripheral T- and NK-cell neoplasias by combination of fluodarabine, cyclophosphamide and doxorubicine.
Onkologie 24:162-164. (2001)

Zunker P, Hohenstein C, Plendl HJ, Zeller JA, Caso V, Georgiadis D, Allardt A, Deuschl G:
Activated protein C resistance and acute iscaemic stroke: Relation to stroke causation and age
J Neurol 248:701-704. (2001)

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2000

Badzioch M, Eeles R, Leblanc G, Foulkes W, Giles G, Edwards S, Goldgar D, Hopper JL, Bishop DT, Möller P, Heimdal K, Easton D, The CRC/BPG UK Familial Prostate Cancer Study Coordinators and Collaborators , The EU Biomed Collaborators, Simard J
Suggestive evidence for a site specific prostate cancer gene on chromosome 1p36.
J Med Genet 37:947-948. (2000)

Bignell GR, Warren W, Seal S, Takahashi M, Rapley E, Barfoot R, Green H, Brown C, Biggs PJ, Lakhani SR, Jones C, Hansen J, Blair E, Hofmann B, Siebert R, Turner G, Evans DG, Schrander-Stumpel C, Beemer FA, van den Ouweland A, Halley D, Delpech B, Cleveland MG, Leigh I, Leisti J, Rasmussen S, Wallace MR, Fenske C, Banerjee P, Oiso N, Chaggar R, Merrett S, Leonard N, Huber M, Hohl D, Chapman P, Burn J, Swift S, Smith A, Ashworth A, Stratton MR:
Identification of the familial cylindromatosis tumour-suppressor gene.
Nat Genet 25:160-165. (2000)

Bohlander SK, Muschinsky V, Schrader K, Siebert R, Schlegelberger B, Harder L, Schemmel V, Fonatsch C, Ludwig WD, Hiddemann W, Dreyling MH
Molecular analysis of the CALM/AF10 fusion: Identical rearrangements in acute myeloid leukemia, acute lymphoblastic leukemia and malignant lymphoma patients.
Leukemia 14:93-99. (2000)

Forrest MS, Edwards SM, Hamoudi RA, Dearnaley DP, Arden-Jones A, Dowe A, Murkin A, Kelly J, Teare MD, Easton DF, Knowles MA, Bishop DT, Eeles RA, The CRC/BPG UK Familial Prostate Cancer Study Collaborators1, The EC Biomed Familial Prostate Cancer Study Collaborators
No evidence of germline PTEN mutations in familial prostate cancer.
J Med Genet 37:210-212. (2000)

Fosså A, Siebert R, Aasheim HC, Maelandsmo GM, Berner A, Fosså SD, Paus E, Smeland EB, Gaudernack G
Identification of nucleolar protein No55 as a tumor-associated autoantigen in patients with prostate cancer.
Br J Cancer 83:743-749. (2000)

Gardner RJ, Mackay DJG, Mungall AJ, Polychronakos C, Siebert R, Shield JPH, Temple IK, Robinson DO
An imprinted locus associated with transient neonatal diabetes mellitus.
Hum Mol Genet 9:589-596. (2000)

Gesk S, Siebert R, Wacker HH, Nürnberg N, Harder L, Lehmann J, Klöppel G, Grote W, Stöckle M, Schlegelberger B
Lack of deletions of the PTEN/MMAC1 and MXI1 loci in renal cell carcinoma by interphase cytogenetics.
Cancer Genet Cytogenet 118:87-88. (2000)

Heidebrecht HJ, Buck F, Pollmann M, Siebert R, Parwaresch R
Cloning and localization of C2orf2ropp120, a previously unknown WD repeat protein.
Genomics 68:348-350.

Hillebrand G, Siebert R, Simeoni E, Santer R
DiGeorge syndrome with discordant phenotype in monocytogic twins.
J Med Genet 37:E23. (2000)

Ma Z, Cools J, Marynen P, Cui X, Siebert R, Gesk S, Schlegelberger B, Peeters B, De Wolf-Peeters C, Wlodarska I, Morris SW
Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis.
Blood 95:2144-2149. (2000)

Pankau R, Partsch CJ, Gosch A, Siebert R, Schneider M, Schneppenheim R, Winter M, Wessel A
Williams-Beuren Syndrome 35 years after the diagnosis in one of the first Beuren patients.
Am J Med Genet 91:322-324. (2000)

Singh R, The ACTANE Consortium
No evidence of linkage to chromosome 1q42.2-43 in 131 prostate cancer families from the ACTANE Consortium.
Br J Cancer 83:1654-1658. (2000)

Takahashi M, Rapley E, Biggs PJ, Lakhani SR, Cooke D, Hansen J, Blair E, Hofmann B, Siebert R, Turner G, Evans DG, Schrander-Stumpel C, Beemer FA, van Vloten WA, Breuning MH, van den Ouweland A, Halley D, Delpech B, Cleveland M, Leigh I, Chapman P, Burn J, Hohl D, Görög JP, Seal S, Mangion J, Warren W, Bignell G, Stratton MR
Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12 - q13.
Hum Genet 106:58-65. (2000)

Zhang Y, Matthiesen P, Harder S, Siebert R, Castoldi G, Calasanz MJ, Wong KF, Rosenwald A, Ott G, Atkin NB, Schlegelberger B
A 3-cM commonly deleted region in 6q21 in leukemias and lymphomas delineated by fluorescence in situ hybridization.
Gene Chromosome Cancer 27:52-58. (2000)

Zhang Y, Siebert R, Matthiesen P, Harder S, Theile M, Scherneck S, Schlegelberger B
Feasibility of simultaneous fluorescence immunophenotyping and fluorescence in situ hybridization study for the detection of estrogen receptor expression and deletions of the estrogen receptor gene in breast carcinoma cell lines.
Virchows Arch 436:271-275. (2000)

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1999

Bräuninger A, Küppers R, Spieker T, Siebert R, Strickler JG, Schlegelberger B, Rajewsky K, Hansmann ML:
Molecular analysis of single B cells from T cell-rich B cell lymphoma reveals the derivation of the tumor cells from mutationg germinal center B cells and exemplifies means by which immunoglobulin genes are modified in germinal center B cells.
Blood 93:2679-2687 (1999)

Rosenwald A, Ott G, Katzenberger T, Siebert R, Kalla J, Kuse R, Ott MM, Müller-Hermelink HK, Schlegelberger B:
Jumping translocation of 1q as the sole aberration in a case of follicular lymphoma.
Cancer Genet Cytogenet 108:53-56 (1999)

Siebert R, Gesk S, Harder L, Steinemann D, Wlodarska I, Tiemann M, Schemmel V, Grote W, Schlegelberger B
Complex variant translocation t(1;2) with TPM3-ALK fusion due to cryptic ALK gene rearrangement in anaplastic large cell lymphoma.
Blood 94:3614-3617. (1999)

Siebert R, Grote W, Schlegelberger B
Familiäres Auftreten hämatologischer Neoplasien.
Société Suisse de Génétique Médicale 41. (1999)

Schlegelberger B, Zwingers T, Harder L, Nowotny H, Siebert R, Vesely M, Bartels H, Sonnen R, Hopfinger G, Nader A, Ott G, Müller-Hermelink K, Feller A, Heinz R for the Kiel-Wien-Lymphoma Study-Group
Clinicopathogenetic significance of chromosomal abnormalities in patients with blastic peripheral B-cell lymphoma.
Blood 94:3114-3120. (1999)

Weimer J, Kiechle M, Senger G, Wiedemann U, Ovens-Raeder A, Schuierer S, Kautza M, Siebert R, Arnold N
An easy and reliable procedure of microdissection technique for the analysis of chromosomal breakpoints and marker chromosomes.
Chrom Res 7:355-362. (1999)

Zhang Q, Siebert R, Yan M, Hinzmann B, Cui X, Xue L, Rakestraw KM, Naeve CW, Beckmann G, Weisenburger DD, Sanger WG, Nowotny H, Vesely M, Callet-Bauchu E, Salles G, Dixit VM, Rosenthal A, Schlegelberger B, Morris SW:
Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32).
Nature Genetics 22:63-68 (1999)

Zhang Y, Heidebrecht HJ, Rott A, Schlegelberger B, Parwaresch R:
Assignment of human proliferation associated p100 gene (C20orf1) to human chromosome band 20q11.2 by in situ hybridization.
Cytogenet Cell Genet 84:182-183 (1999)

Zhang Y, Kreder D, Schwandner R, Krut O, Scherer G, Adam-Klages S, Siebert R, Krönke M, Schlegelberger B
Assignment of the human FAN protein gene (NSMAF) to human chromosome region 8q12®q13 by in situ hybridization.
Cytogenet Cell Genet 87:115-116. (1999)

Zhang Y, Wong KF, Siebert R, Matthiesen P, Harder S, Eimermacher H, Feller AC, Schlegelberger B:
Chromosome aberrations are restricted to the CD56+, CD3- tumor cell population in natural killer cell lymphomas: A combined immunophenotyping and FISH study.
Br J Haematol 105:737-742 (1999)

 

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1998

Campo E, Gaulard P, Zucca E, Jaffe ES, Harris NL, Diebold J, Schlegelberger B, Feller AC, Delsol G, Gisselbrecht C, Monserrat E:
Report of the European Task Force on lymphomas: workshop on peripheral T-cell lymphomas.
Ann Oncol 9:835-843 (1998)

Dreyling MH, Schrader K, Fonatsch C, Schlegelberger B, Haase D, Schoch C, Ludwig WD, Löffler H, Büchner T, Wörmann B, Hiddemann W, Bohlander SK:
MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11) – both rearrangements are associated with a poor prognosis.
Blood 91:4662-4667 (1998)

Haferlach T, Löffler H, Nickenig C, Ramm-Petersen L, Meeder M, Schoch R, Schlegelberger B, Schnittger S, Schoch C, Hiddemann W:
Cell lineage specific involvement in acute promyelocytic leukemia (APL) using a combination of May-Grünwald Giemsa staining and fluorescence in situ hybridization techniques for the detection of the translocation t(15;17).
Br J Hematol 103:93-99 (1998)

Ott G, Katzenberger T, Siebert R, DeCoteau J F , Fletcher J A, Knoll J H M, Kalla J, Rosenwald A, Ott M M, Weber-Matthiesen K, Kadin M E, Müller-Hermelink H K:
Chromosomal abnormalities in nodal and extranodal CD30+ anaplastic large cell lymphomas: infrequent detection of the t(2;5) in extranodal lymphomas.
Genes, Chromosomes and Cancer 22: 114-121 (1998).

Siebert R, Gesk S, Harder S, Plötz S, Matthiesen P, Jandrig B, Grasmo-Wendler UH, Scherneck S, Rosenwald A, Ott G, Schlegelberger B:
Deletions in the long arm of chromosome 10 in lymphomas with t(14;18): a pathogenetic role of the tumor suppressor genes PTEN/MMAC1 and MXI1?
Blood, 92:4487-4489 (1998)

Zhang Y, Matthiesen P, Siebert R, Harder S, Theile M, Scherneck S, Schlegelberger B:
Detection of 6q deletions in breast carcinoma cell lines by fluorescence in situ hybridization (FISH).
Hum. Genet. 103:727-729 (1998)

Siebert R, Jacobi C, Matthiesen P, Zuehlke-Jenisch R, Potratz C, Zhang Y, Stöckle M, Klöppel G & Schlegelberger B:
Detection of deletions in the short arm of chromosome 3 in unculltured renal cell carcinomas by interphase cytogenetics.
Journal of Urology 160:534-539 (1998)

Siebert R, Matthiesen P, Harder S, Zhang Y, Borowski A, Zuehlke R, Metzke S, Joos S, Weber-Matthiesen K, Grote W, Schlegelberger B:
Application of interphase fluorescence in situ hybridization for the detection of the Burkitt translocation t(8;14)(q24;q32) in B-cell lymphomas.
Blood 91:984-990 (1998)

Siebert R, Matthiesen P, Harder S, Zhang Y, Borowski A, Zühlke-Jenisch R, Plendl H, Metzke S, Joos S, Zucca E, Weber-Matthiesen K, Cavalli F, Grote W, Schlegelberger B:
Application of interphase cytogenetics for the detection t(11;14)(q13;q32) in mantle cell lymphomas.
Annals of Oncology 9:519-526 (1998)

Schlegelberger B:
Zytogenetische Diagnostik bei Leukämien und malignen Lymphomen. In: Bruhn HD, Fölsch UR (ed): Lehrbuch der Laboratoriumsmedizin.
Schattauer, Stuttgart, New York, im Druck

Schlegelberger B, Siebert R Grote W:
Genetische Beratung bei erblichen Krebserkrankungen.
Schleswig-Holsteinisches Ärzteblatt 5: 25-28 (1998)

Wagner HJ, Klintworth F, Jabs W, Lange K, Harder L, Schlegelberger B, Feller AC, Bucsky P:
Characterization of the novel, pediatric Hodgkin´s tissue derived cell line HKB-1.
Med Ped Oncol 31:138-143 (1998)

Zhang Y, Cai X, Schlegelberger B, Zheng S:
Assignment of human putative tumor suppressor genes ST13 (alias SNC6) and ST14 (alias SNC19) to human chromosome bands 22q13 and 11q24-q25 by in situ hybridization.
Cytogenet Cell Genet 83:56-57 (1998)

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1997

Haferlach T, Winkemann M, Nickenig C, Meeder M, Ramm-Petersen L, Schoch R, Nickelsen M, Weber-Matthiesen K, Schlegelberger B, Schoch C, Gassmann W, Löffler H: Which compartments are involved in Phildalphia-chromosome positive chonic myeloid leukaemia? An answer at the single cell level by combining May-Grünwald-Giemsa staining and fluorescence in situ hybridization techniques. Br J Haematol 97:99-106 (1997)

Haferlach T, Winkemann M, Ramm-Petersen L, Meeder M, Schoch R, Weber-Matthiesen K, Schlegelberger B, Schoch Claudia, Ludwig WD: New insights into the biology of Philadelphia-chromosome-positive acute lymphoblastic leukaemia using a combination of May-Grünwald-Giemsa staining and fluorescence in situ hybridization techniques at the single cell level. Br J Haematol 99:452-459 (1997)

Harder J, Siebert R, Zhang Y, Matthiesen P, Christophers E, Schlegelberger B, Schröder JM: Mapping of the gene encoding human beta-defensin-2 (DEFB2) to chromosome region 8p22-p23.1. Genomics 46:472-475 (1997)

Rowley JD, Reshmi S, Sobulo O, Musvee T, Anastasi J, Raimondi S, Schneider NR, Barredo JC, Cantu ES, Schlegelberger B, Behm F, Doggett NA, Borrow J, Zeleznik-Le N: All patients with the t(11;16)(q23;p13.3) which involves MLL and CBP treatment-related hematologic disorders. Blood 90:535-541 (1997)

Schoch C, Haase D, Fonatsch C, Haferlach T, Löffler H, Schlegelberger B, Hossfeld DK, Becher R, Sauerland MC, Heinecke A, Wörmann B, Büchner T, Hiddemann W: The significance of trisomy 8 in de novo acute myeloid leukemia: the accompanying chromosome aberrations determine the prognosis. Br J Haematol 99:605-611 (1997)

Siebert R, Gesk S, Harder L, Steinemann D, Wlodarska I, Tiemann M, Schemmel V, Grote W, Schlegelberger B: Complex variant translocation t(1;2) with TPM3-ALK fusion due to cryptic ALK gene rearrangement in anaplastic large cell lymphoma. Blood 94:3614-3617. (1999)

Siebert R, Schlegelberger B: Combined fluorescence immunophenotyping and interphase cytogenetics in malignant lymphomas: Results from FICTION studies. Rev Clin Exp Hematol 4:41-55 (1997)

Siebert R, Weber-Matthiesen K, Matthiesen P, Zhang Y, Schlegelberger B:Re: B-cell Non-Hodgkin's lymphoma: Evidence for the t(14;18) translocation in all hematopoietic cell lineages (letter). Journal of the National Cancer Institute 89: 93-94 (1997).

Sobulo OM, Borrow J, Tomek R, Reshmi S, Harden A, Schlegelberger B, Housman D, Doggett NA, Rowley JD, Zeleznik-Le NJ: MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3). Proc Natl Acad Sci 94:8732-8737 (1997)

Zhang Y, Weber-Matthiesen K, Schlegelberger B: Frequent deletions of 6q23-24 in B-cell Non-Hodgkin´s lymphomas detected by fluorescence in situ hybridization. Genes Chrom Cancer 18:310-313 (1997)

Zhang Y, Weber-Matthiesen K, Schoch R, Schlegelberger B: Variant Philadelphia translocation t(9;17)(q34.2-3;q21.3) with colocalization of the bcr and abl genes on chromosome 9 in chronic myeloid leukemia. Cancer Genet Cytogenet 96:87-89 (1997)

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1996

Zhang Y, Poetsch M, Weber-Matthiesen K, Rohde K, Winkemann M, Haferlach T, Gassmann W, Ludwig W-D, Grote W, Löffler H, Schlegelberger B: Secondary acute leukaemias with 11q23 rearrangement: clinical, cytogenetic, FISH and FICTION studies. Br J Haematol 92:673-680 (1996)

Schlegelberger B, Zwingers T, Hohenadel K, Henne-Bruns D, Schmitz N, Haferlach T, Tirier C, Bartels H, Sonnen R, Kuse R, Grote W: Significance of cytogenetic findings for the clinical outcome in patients with T cell lymphoma of AILD-type. J Clin Oncol 14:593-599 (1996) Schlegelberger B, Feller AC: Classification of peripheral T-cell lymphomas: Cytogenetic findings support the updated Kiel classification. Leuk Lymphoma 20:411-416 (1996)

Tirier C, Zhang Y, Plendl H, Weber-Matthiesen K, Langer W, Heit W, Schlegelberger B: Simultaneous presence of t(11;14) and a variant Burkitt´s translocation in the terminal phase of a mantle cell lymphoma. Leukemia 10:346-350 (1996)

Poetsch M, Weber-Matthiesen K, Plendl HJ, Grote W, Schlegelberger B: Detection of the t(14;18) chromosomal translocation by interphase cytogenetics with yeast-artificial-chromosome probes in follicular lymphoma and nonneoplastic lymphoproliferation. J Clin Oncol 14:963-969 (1996)

Deerberg-Wittram J, Weber-Matthiesen K, Schlegelberger B: Cytogenetics and molecular cytogenetics in Hodgkin´s disease. Ann Oncol 7:49-53 (1996)

Weber-Matthiesen K, Deerberg-Wittram J, Rosenwald A, Poetsch M, Grote W, Schlegelberger B: The translocation t(2;5) is not a primary event in hodgkin´s disease: Simultaneous immunophenotyping and interphase cytogenetics. Am J Pathol 149:463-468 (1996)

Weber-Matthiesen K, Deerberg-Wittram J, Schlegelberger B: Truth by FICTION. Blood 87:4479-4480 (1996)

Schlegelberger B, Zhang Y, Weber-Matthiesen K, Zwingers T: Cytogenetic findings in T cell lymphoma of angioimmunoblastic lymphadenopathy. J Clin Oncol 14:2188-2189 (1996)

Haferlach T, Bennett JM, Löffler H, Gassmann W, Andersen JW, Tuzuner N, Casslleth PA, Fonatsch C, Schoch C, Schlegelberger B, Becher R, Thiel E, Ludwig WD, Sauerland MC, Heinecke A, Büchner T: Acute myeloid leukemia with translocation (8;21). Cytomorphology, dysplasia and prognostic factors in 41 cases. Leuk Lymphoma 23:227-234 (1996)

Stilgenbauer S, Liebisch P, James MR, Schröder M, Schlegelberger B, Fischer K, Bentz M, Lichter P, Döhner H: Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-23.1 in lymphoproliferative disorders. Proc Natl Acad Sci 93:11837-11841 (1996)

Siebert R, Weber-Matthiesen K, Matthiesen P, Zhang Y, Schlegelberger B: Re: B-cell non-Hodgkin's lymphoma: Analysis of the t(14;18) translocation in different hematopoietic cell lineages. J Natl Cancer Inst 89:93-94 (1996)

Haferlach T, Winkemann M, Löffler H, Schoch R, Gassmann W, Fonatsch C, Schoch C, Poetsch M, Weber-Matthiesen K, Schlegelberger B: The abnormal eosinophils are part of the leukemic cell population in acute myelomonocytic leukemia with abnormal eosinophils (AML M4Eo) and carry the pericentric inversion 16: a combination of May-Grünwald-giemsa staining and fluorescence in situ hybridization. Blood 87:2459-2463 (1996)

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1995

Zucca E, Soldati G, Schlegelberger B, Booth MJ, Weber-Matthiesen K, Cavalli F, Cotter FE: Detection of chromosome 11 alterations in blood and bone marrow by interphase cytogenetics in mantle cell lymphoma. Br J Haematol 89:665-668 (1995)

Behrendt H, Charrin C, Gibbons B, Harrison CJ, Hawkins JM, Heerema NA, Horschler-Bötel B, Huret JL, Lai JL, Lampert F, Nelken B, Perot C, Ritterbach J, Schlegelberger B, Secker-Walker L, Slater R, Slovak ML, Tanzer J, Van Den Akker J: Dicentric (9;12) in acute lymphocytic leukemia and other hematological malignancies: Report from a dic (9;12) study group. Leukemia 9:102-106 (1995)

Merz H, Orscheschek K, Schlegelberger B, Feller AC: Large-cell anaplastic lymphoma-specific translocation (t[2;5][p23;q35] in Hodgkin´s disease: indication of a common pathogenesis). Authors' reply. Lancet 345:920 (1995)

Weber-Matthiesen K, Deerberg J, Poetsch M, Grote W, Schlegelberger B: Clarification of dubious karyotypes in Hodgkin´s disease by simultaneous fluorescence immunophenotyping and interphase cytogenetics (FICTION). Cytogenet Cell Genet 70:243-245 (1995)

Weber-Matthiesen K, Deerberg J, Poetsch M, Grote W, Schlegelberger B: Numerical chromosome aberrations are present within the CD30-positive Hodgkin and Reed-Sternberg cells in 100% of analysed cases of Hodgkin´s disease. Blood 86:1464-1468 (1995)

Weber Matthiesen K, Winkemann M, Grote W, Schlegelberger B: Kappa and lambda positive cells in centroblastic-centrocytic lymphoma (follicular lymphoma) may share the same secondary chromosome aberration: Reflections on early lymphoma development. Genes Chrom Cancer 14:22-27 (1995)

Bullrich F, Druck T, Kunapuli P, Gomez J, Gripp KW, Schlegelberger B, Lasota J, Aronson M, Cannizzaro LA, Huebner K, Benovic JL : Chromosomal mapping of the genes GPRK5 and GRPK6 encoding G protein-coupled receptor kinases GRK5 and GRK6. Cytogenet Cell Genet 70:250-254 (1995)

Bentz M, Döhner H, Werner CA, Huck K, Baudis M, Joos S, Schlegelberger B, Trümper LH, Feller AC, Pfreundschuh M, Möller P, Lichter P: Identification of genetic imbalances in malignant lymphoma using comparative genomic hybridization. Stem cells 13:83-87 (1995)

Zhang Y, Weber-Matthiesen K, Schlegelberger B: High frequency of oligoclonal proliferations in AILD-type T cell lymphomas detected by interphase cytogenetics. "The four Ts: T-cell, tolerance, transplantation and tumor",Pabst Science Publisher, Lengerich, Berlin, Prag, Riga, Wien, Zagreb, 1995

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1994

Schlegelberger B, Weber-Matthiesen K, Himmler A, Eumann S, Bartels H, Sonnen R, Kuse R, Feller AC, Grote W: Cytogenetic findings and results of combined immunophenotyping and karyotyping in Hodgkin's disease. Leukemia 8:72-80 (1994)

Schlegelberger B, Himmler A, Gödde E, Grote W, Feller AC, Lennert K: Cytogenetic findings in peripheral T cell lymphomas as a basis for distinguishing low grade and high grade lymphomas. Blood 83:505-511 (1994)

Bucsky P, Favara B, Feller AC, Nezelof C, Radzun HJ, Schlegelberger B, Janka- Schaub G: Malignant histiocytosis and large cell anaplastic (Ki-1) lymphoma in childhood: Guidelines for differential diagnosis - Report of the Histiocyte Society. Med Pediatr Oncol 22:200-203 (1994)

Schlegelberger B, Weber-Matthiesen K, Sterry W, Bartels H, Grote W: Combined immunophenotyping and karyotyping in peripheral T cell lymphomas demonstrating different clonal and nonclonal chromosome aberrations in T helper cells. Leuk Lymphoma 15:113-125 (1994)

Schlegelberger B, Bartels H, Sterry W: Chromosomal evolution in a Merkel cell carcinoma. Cancer Genet Cytogenet 75:74-76 (1994)

Schlegelberger B, Zhang Y, Weber-Matthiesen K, Grote W: Detection of aberrant clones in nearly all cases of angioimmunoblastic lymphadenopathy with dysproteinemia-type T cell lymphoma by combined interphase and metaphase cytogenetics. Blood 84:2640-2648 (1994)

Schlegelberger B, Himmler A, Bartels H, Kuse R, Sterry W, Grote W: Recurrent chromosome abnormalities in peripheral T cell lymphomas. Cancer Genet Cytogenet 78:15-22 (1994)

Zhang Y, Schlegelberger B, Weber-Matthiesen K, Grote W, Bartels H: Translocation t(X;8)(q2?6;q21.3) in a case of systemic mastocytosis. Cancer Genet Cytogenet 78:236-238 (1994)

Orscheschek K, Merz H, Schlegelberger B, Feller AC: An immortalized cell line with features of human follicular dendritic cells. Antigen and cytokine expression analysis. Eur J Immunol 24:2682-2690 (1994)

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1993

Schlegelberger B, Bartels H, Wacker HH, Grote W: t(2;3)(p12;q27) in Hodgkin's disease of an HIV-positive haemophiliac. Blood 81:265-266 (1993)

Weber-Matthiesen K, Pressl S, Schlegelberger B, Grote W: Combined immunophenotyping and interphase cytogenetics on caryostat section by the new FICTION-method. Leukemia 7:646-649 (1993)

Weber-Matthiesen K, Deerberg J, Müller-Hermelink A, Schlegelberger B, Grote W: Rapid immunophenotypic characterization of chromosomally aberrant cells by the new FICTION method. Cytogenet Cell Genet 63:123-125 (1993)

Zhang Y, Schlegelberger B, Plendl HJ, Sonnen R, Kuse R, Feller AC, Grote W: Clonal t(8;14)(p11;q31) in a case of reactive lymphoproliferation. Genes Chrom Cancer 7:165-168 (1993)

Haferlach T, Gassmann W, Löffler H, Jürgensen C, Noak J, Ludwig WD, Thiel E, Haase D, Fonatsch C, Becher R, Schlegelberger B, Nowrousian MR, Lengfelder E, Eimermacher H, Weh HJ, Braumann D, Maschmeyer G, Koch P, Heinecke A, Sauerland MC, Büchner T: Clnical aspects of acute myeloid leukemias of the FAB types M3 and M4Eo. Ann Hematol 66:165-170 (1993)

Weber-Matthiesen K, Deerberg J, Müller-Hermelink A, Winkemann M, Schlegelberger B, Grote W: Rationalization of in situ hybridization: Testing up to 16 different probes on a single slide. Cancer Genet Cytogenet 68:91-94 (1993)

Weber-Matthiesen K, Müller-Hermelink A, Deerberg J, Scherthan H, Schlegelberger B, Grote W: Discrimination of distinct subpopulations within a tumor using combined double immunophenotyping and interphase cytogenetics. J Histochem Cytochem 41:1641-1644 (1993)

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1992

Schlegelberger B, Weber-Matthiesen K, Eumann S., Rathjen M, Grote W: Detection of structural chromosome aberrations in immunophenotyped mitoses. Cytogenet Cell Genet 59:10-11 (1992)

Weber-Matthiesen K, Winkemann M, Müller-Hermelink A, Schlegelberger B, Grote W: Simultaneous fluorescence immunophenotyping and interphase cytogenetics: A contribution to the characterization of tumor cells. J Histochem Cytochem 40:171-175 (1992)

Schmitz N, Suttorp M, Schlegelberger B, Weber-Matthiesen K, Tiemann M, Sonnen R: The role of the spleen after bone marrow transplantation for primary myelofibrosis. Br J Haematol 81:617-618 (1992)

Schlegelberger B: Zytogenetik maligner Lymphome. Verh Dtsch Ges Path 76:60-65 (1992)

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1991

Schlegelberger B: Stufenweise Entwicklung der Chromosomenaberrationen bei der angioimmmunoblastischen Lymphadenopathie (AILD). Schl Holst Ärztebl 5:37-42 (1991)

Schlegelberger B: Klinische Bedeutung und molekulare Grundlagen von Chromosomenaberrationen bei malignen Lymphomen. Med Klin 86:360-366 (1991)

Schlegelberger B, Grote W, Sterry W: An identical chromosome abnormality der(6)t(6;7)(q13;p13) in two patients with peripheral T cell lymphoma. Cancer Genet Cytogenet 54:269-272 (1991)

Schmitz N, Schlegelberger B, Oberböster K, Golchert K, Suttorp M, Löffler H: Lymphohaematopoietic chimaerism after bone marrow transplantation for chronic myeloid leukaemia: Results of simultaneous cytogenetic analyses on T-cell colonies, myeloid, and erythroid progenitor cells. Br J Haematol 78:334-342 (1991)

Schmitz N, Prange E, Haferlach T, Griesser H, Sonnen R, Schlegelberger B, Claus S, Löffler H: High-dose chemotherapy and autologous bone marrow transplantation in relapsing angioimmunoblastic lymphadenopathy with dysproteinemia (AILD). Bone marrow transplant 8:503-506 (1991)

Grundy C, Plendl H, Grote W, Zoll B, Kakkar V V, Cooper D N: A single Base-Pair Deletion in the Protein C Gene Causing Recurrent Thrombembolism. Thromb. Res. 61 (1991), 335-340.

Wiechen K, Plendl H, Grote W: Isoelectric Focusing Pattern of Human Amniotic Fluid AFP. Prenat. Diagn. 11 (1991), 427-435.

Wiechen K, Plendl H, Grote W: Isoelectric focusing of amniotic fluid a-fetoprotein to improve diagnosis of neural tube defects. Lancet 1991; 337: 674.

Plendl H, Hedderich J, Grote W: Computer Aided Diagnosis of Haemostatic disorders. Annals of Hematology (1991).

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1990

Schlegelberger B, Feller AC, Wacker H-H, Lohmeyer J, Grote W: Inv(14) with distal breakpoint in 14q32.1 in three cases of T cell lymphoma. Hum Genet 85:80-84 (1990)

Schlegelberger B, Feller A, Himmler A, Grote W: Inv(14)(q11q32) in one of four different clones in a case of angioimmunoblastic lymphadenopathy (AILD). Cancer Genet Cytogenet 44:77-81 (1990)

Schlegelberger B, Feller A, Gödde E, Grote W, Lennert K: Stepwise development of chromosomal abnormalities in angioimmunoblastic lymphadenopathy (AILD). Cancer Genet Cytogenet 50:15-29 (1990)

Schlegelberger B, Nölle I, Feller A, Bauer E, Grote W: Angioimmunoblastic lymphadenopathy with trisomy 3: Cells of the malignant clone are T cells. Hematol Pathol 4:179-183 (1990)

Budde U, Schneppenheim R, Plendl H, Dent J, Ruggeri Z M, Zimmerman T S: Luminographic Detection of von Willebrand Factor Multimers in Agarose Gels and on Nitrocellulose Membranes. Thrombos. Haemostas. 63 (1990), 312-315.

Schneppenheim R, Plendl H, Ewerhardt B, Olek K, Bruhn H. D. (Hrsg.): Untersuchungen zur Molekularbiologie des von Willebrand- Syndroms. 6. Kongreß der Gesellschaft für Thrombose- und Hämostaseforschung. Stuttgart, New York: Schattauer 1990: 265 - 268.

Wiechen K, Plendl H, Grote W: Human Amniotic Fluid alpha - Fetoprotein Analysis by Isoelectric Focusing and Immunoblotting in Prenatal Diagnosis. Abstracts: Gesellschaft für Humangenetik, 2. Tagung Bonn 1990 (1990), 304.

Plendl H, Wiechen K, Grote W: Isoelectric Focusing of Amniotic Fluid alpha - Fetoprotein Improves Screening for Open Neural Tube Defects: Early Fetal Diagnosis and Public Health Impact. Macek M., Ferguson-Smith M.A., Spála M. (Eds.). Karolinum - Charles University Press, Prague (1990).

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