CAU Logo
Christian–Albrechts–Universität zu Kiel
Institut für Medizinische Informatik und Statistik

Publications by Amke Caliebe

Aramillo Irizar P, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C.
Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.
Nat Commun, 9 (2018), 327.  [abstract]

Caliebe A, Krawczak M, Kayser M.
Predictive values in Forensic DNA Phenotyping are not necessarily prevalence-dependent.
Forensic Sci Int Genet, 33 (2018), e7-e8. 

Schottler J, Randoll N, Lucius R, Caliebe A, Roider J, Klettner A.
Long-term treatment with anti-VEGF does not induce cell aging in primary retinal pigment epithelium.
Exp Eye Res, (2018).  [abstract]

Morrison GS, Kaye DH, Balding DJ, Taylor D, Dawid P, Aitken CG, Gittelson S, Zadora G, Robertson B, Willis S, Pope S, Neil M, Martire KA, Hepler A, Gill RD, Jamieson A, de Zoete J, Ostrum RB, Caliebe A.
A comment on the PCAST report: Skip the "match"/"non-match" stage.
Forensic Sci Int, 272 (2017), e7-e9.  [abstract]

Flachsbart F, Dose J, Gentschew L, Geismann C, Caliebe A, Knecht C, Nygaard M, Badarinarayan N, ElSharawy A, May S, Luzius A, Torres GG, Jentzsch M, Forster M, Häesler R, Pallauf K, Lieb W, Derbois C, Galan P, Drichel D, Arlt A, Till A, Krause-Kyora B, Rimbach G, Blanché H, Deleuze JF, Christiansen L, Christensen K, Nothnagel M, Rosenstiel P, Schreiber S, Franke A, Sebens S, Nebel A.
Identification and characterization of two functional variants in the human longevity gene FOXO3.
Nat Commun, 8 (2017), 2063.  [abstract]

Jüptner M, Flachsbart F, Caliebe A, Lieb W, Schreiber S, Zeuner R, Franke A, Schröder JO.
Low copy numbers of complement C4 and homozygous deficiency of C4A may predispose to severe disease and earlier disease onset in patients with systemic lupus erythematosus.
Lupus, (2017), 961203317735187.  [abstract]

Fudickar A, Gruenewald M, Fudickar B, Hill M, Wallenfang M, Hüllemann J, Voss D, Caliebe A, Roider JB, Steinfath M, Treumer F.
Immobilisation during anaesthesia for vitrectomy using a laryngeal mask without neuromuscular blockade versus endotracheal intubation and neuromuscular blockade.
Minerva Anestesiol, (2017).  [abstract]

Knecht C, Mort M, Junge O, Cooper DN, Krawczak M, Caliebe A.
IMHOTEP-a composite score integrating popular tools for predicting the functional consequences of non-synonymous sequence variants.
Nucleic Acids Res, 45 (2017), e13. 

Caliebe A, Nebel A, Makarewicz C, Krawczak M, Krause-Kyora B.
Insights into early pig domestication provided by ancient DNA analysis.
Sci Rep, 7 (2017), 44550.  [abstract]

Saeger M, Heckmann J, Purtskhvanidze K, Caliebe A, Roider J, Koinzer S.
Variability of panretinal photocoagulation lesions across physicians and patients. Quantification of diameter and intensity variation.
Graefes Arch Clin Exp Ophthalmol, 255 (2017), 49-59.  [abstract]

Cavus E, Janssen S, Reifferscheid F, Caliebe A, Callies A, von der Heyden M, Knacke PG, Doerges V.
Videolaryngoscopy for Physician-Based, Prehospital Emergency Intubation: A Prospective, Randomized, Multicenter Comparison of Different Blade Types Using A.P. Advance, C-MAC System, and KingVision.
Anesth Analg, (2017).  [abstract]

Caliebe A, Walsh S, Liu F, Kayser M, Krawczak M.
Likelihood ratio and posterior odds in forensic genetics: Two sides of the same coin.
Forensic Sci Int Genet, 28 (2017), 203-210.  [abstract]

Wolfart S, Wolf K, Brunzel S, Wolfart M, Caliebe A, Kern M.
Implant placement under existing removable dental prostheses and its effect on masticatory performance.
Clin Oral Investig, 20 (2016), 2447-2455.  [abstract]

Caliebe A, Krawczak M.
Probability and Likelihood.
In: Handbook of Forensic Genetics: Biodiversity and Heredity in Civil and Criminal Investigation, Publisher: World Scientific, New Jersey, Editors: Antonio Amorim, Bruce Budowle, (2016), 61-80.  [abstract]

Flachsbart F, Ellinghaus D, Gentschew L, Heinsen FA, Caliebe A, Christiansen L, Nygaard M, Christensen K, Blanché H, Deleuze JF, Derbois C, Galan P, Büning C, Brand S, Peters A, Strauch K, Müller-Nurasyid M, Hoffmann P, Nöthen MM, Lieb W, Franke A, Schreiber S, Nebel A.
Immunochip analysis identifies association of the RAD50/IL13 region with human longevity.
Aging Cell, 15 (2016), 585-8.  [abstract]

Caliebe A, Harder M, Schuett R, Krawczak M, Nebel A, von Wurmb-Schwark N.
The more the merrier? How a few SNPs predict pigmentation phenotypes in the Northern German population.
Eur J Hum Genet, 24 (2016), 739-47.  [abstract]

Koinzer S, Baade A, Schlott K, Hesse C, Caliebe A, Roider J, Brinkmann R.
Temperature-Controlled Retinal Photocoagulation Reliably Generates Uniform Subvisible, Mild, or Moderate Lesions.
Transl Vis Sci Technol, 4 (2015), 9.  [abstract]

Caliebe A, Jochens A, Willuweit S, Roewer L, Krawczak M.
No shortcut solution to the problem of Y-STR match probability calculation.
Forensic Sci Int Genet, 15 (2015), 69-75.  [abstract]

Bruckmueller H, Werk AN, Renders L, Feldkamp T, Tepel M, Borst C, Caliebe A, Kunzendorf U, Cascorbi I.
Which Genetic Determinants Should be Considered for Tacrolimus Dose Optimization in Kidney Transplantation? A Combined Analysis of Genes Affecting the CYP3A Locus.
Ther Drug Monit, 37 (2015), 288-95.  [abstract]

Däumer C, Flachsbart F, Caliebe A, Schreiber S, Nebel A, Krawczak M.
Adjustment for smoking does not alter the FOXO3A association with longevity.
Age (Dordr), 36 (2014), 911-21.  [abstract]

Koinzer S, Bajorat S, Hesse C, Caliebe A, Bever M, Brinkmann R, Roecken C, Roider J.
Calibration of histological retina specimens after fixation in Margo's solution and paraffin embedding to in-vivo dimensions, using photography and optical coherence tomography.
Graefes Arch Clin Exp Ophthalmol, 252 (2014), 145-53.  [abstract]

Koinzer S, Caliebe A, Portz L, Saeger M, Miura Y, Schlott K, Brinkmann R, Roider J.
Comprehensive detection, grading, and growth behavior evaluation of subthreshold and low intensity photocoagulation lesions by optical coherence tomographic and infrared image analysis.
Biomed Res Int, 2014 (2014), 492679.  [abstract]

Flachsbart F, Caliebe A, Heinsen FA, Hemming-Karlsen T, Schreiber S, Franke A, Nebel A.
Investigation of complement component C4 copy number variation in human longevity.
PLoS One, 9 (2014), e86188.  [abstract]

Wang L, Wenners A, Hilpert F, Fredrik R, Micci F, Onkes W, Caliebe A, Maass N, Weimer J, Arnold N.
Frequent translocations of 11q13.2 and 19p13.2 in ovarian cancer.
Genes Chromosomes Cancer, 53 (2014), 447-53.  [abstract]

Deelen J, Beekman M, Uh HW, Broer L, Ayers KL, Tan Q, Kamatani Y, Bennet AM, Tamm R, Trompet S, Guðbjartsson DF, Flachsbart F, Rose G, Viktorin A, Fischer K, Nygaard M, Cordell HJ, Crocco P, van den Akker EB, Böhringer S, Helmer Q, Nelson CP, Saunders GI, Alver M, Andersen-Ranberg K, Breen ME, van der Breggen R, Caliebe A, Capri M, Cevenini E, Collerton JC, Dato S, Davies K, Ford I, Gampe J, Garagnani P, de Geus EJ, Harrow J, van Heemst D, Heijmans BT, Heinsen FA, Hottenga JJ, Hofman A, Jeune B, Jonsson PV, Lathrop M, Lechner D, Martin-Ruiz C, Mcnerlan SE, Mihailov E, Montesanto A, Mooijaart SP, Murphy A, Nohr EA, Paternoster L, Postmus I, Rivadeneira F, Ross OA, Salvioli S, Sattar N, Schreiber S, Stefánsson H, Stott DJ, Tiemeier H, Uitterlinden AG, Westendorp RG, Willemsen G, Samani NJ, Galan P, Sørensen TI, Boomsma DI, Jukema JW, Rea IM, Passarino G, de Craen AJ, Christensen K, Nebel A, Stefánsson K, Metspalu A, Magnusson P, Blanché H, Christiansen L, Kirkwood TB, van Duijn CM, Franceschi C, Houwing-Duistermaat JJ, Slagboom PE.
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.
Hum Mol Genet, 23 (2014), 4420-32.  [abstract]

Schulz T, Pries A, Caliebe A, Kapischke M.
Long-term survival after simultaneous pancreas-kidney transplantation with primary function of at least one year - a single-center experience.
Ann Transplant, 19 (2014), 106-11.  [abstract]

Koinzer S, Hesse C, Caliebe A, Saeger M, Baade A, Schlott K, Brinkmann R, Roider J.
Photocoagulation in rabbits: Optical coherence tomographic lesion classification, wound healing reaction, and retinal temperatures.
Lasers Surg Med, 45 (2013), 427-36.  [abstract]

Moritz JD, Hoffmann B, Sehr D, Caliebe A, Groth G, Heller M, Bolte H.
[Comparison of MRI and CT for assessment of childhood fractures: studies on a porcine model].
Unfallchirurg, 116 (2013), 916-22.  [abstract]

Ma Y, Weimer J, Fredrik R, Adam-Klages S, Sebens S, Caliebe A, Hilpert F, Eckmann-Scholz C, Arnold N, Schem C.
Aurora kinase inhibitor AZD1152 has an additional effect of platinum on a sequential application at the human ovarian cancer cell line SKOV3.
Arch Gynecol Obstet, 288 (2013), 173-82.  [abstract]

Kapischke M, Pries A, Caliebe A.
Short term and long term results after open vs. laparoscopic appendectomy in childhood and adolescence: a subgroup analysis.
BMC Pediatr, 13 (2013), 154.  [abstract]

Flachsbart F, Möller M, Däumer C, Gentschew L, Kleindorp R, Krawczak M, Caliebe A, Schreiber S, Nebel A.
Genetic investigation of FOXO3A requires special attention due to sequence homology with FOXO3B.
Eur J Hum Genet, 21 (2013), 240-2.  [abstract]

Andersen MM, Caliebe A, Jochens A, Willuweit S, Krawczak M.
Estimating trace-suspect match probabilities for singleton Y-STR haplotypes using coalescent theory.
Forensic Sci Int Genet, 7 (2013), 264-71.  [abstract]

Koinzer S, Schlott K, Ptaszynski L, Bever M, Kleemann S, Saeger M, Baade A, Caliebe A, Miura Y, Birngruber R, Brinkmann R, Roider J.
Temperature-controlled retinal photocoagulation - a step toward automated laser treatment.
Invest Ophthalmol Vis Sci, 53 (2012), 3605-14.  [abstract]

Moritz JD, Hoffmann B, Sehr D, Keil K, Eggerking J, Groth G, Caliebe A, Dischinger J, Heller M, Bolte H.
Evaluation of Ultra-Low Dose CT in the Diagnosis of Pediatric-Like Fractures Using an Experimental Animal Study.
Korean J Radiol, 13 (2012), 165-73.  [abstract]

Moritz JD, Hoffmann B, Sehr DH, Eggerking J, Keil K, Caliebe A, Dischinger J, Heller M, Bolte H.
[Pediatric fracture diagnosis--ultra-low-dose CT with an effective dose equal to that of radiographs].
Rofo, 184 (2012), 1026-33.  [abstract]

Koinzer S, Schlott K, Portz L, Ptaszynski L, Baade A, Bever M, Saeger M, Caliebe A, Denner R, Birngruber R, Brinkmann R, Roider J.
Correlation of temperature rise and optical coherence tomography characteristics in patient retinal photocoagulation.
J Biophotonics, 5 (2012), 889-902.  [abstract]

Broch O, Renner J, Gruenewald M, Meybohm P, Schöttler J, Caliebe A, Steinfath M, Malbrain M, Bein B.
A comparison of the Nexfin® and transcardiopulmonary thermodilution to estimate cardiac output during coronary artery surgery.
Anaesthesia, 67 (2012), 377-83.  [abstract]

Willuweit S, Caliebe A, Andersen MM, Roewer L.
Y-STR Frequency Surveying Method: A critical reappraisal.
Forensic Sci Int Genet, 5 (2011), 84-90.  [abstract]

von Wurmb-Schwark N, Caliebe A, Schwark T, Kleindorp R, Poetsch M, Schreiber S, Nebel A.
Association of TH01 with human longevity revisited.
Eur J Hum Genet, 19 (2011), 924-7.  [abstract]

Gruenewald M, Meybohm P, Broch O, Caliebe A, Koerner S, Renner J, Steinfath M, Bein B.
Visual evaluation of left ventricular performance predicts volume responsiveness early after resuscitation from cardiac arrest.
Resuscitation, 82 (2011), 1553-7.  [abstract]

Kapischke M, Friedrich F, Hedderich J, Schulz T, Caliebe A.
Laparoscopic versus open appendectomy--quality of life 7 years after surgery.
Langenbecks Arch Surg, 396 (2011), 69-75.  [abstract]

Gräsner JT, Meybohm P, Caliebe A, Böttiger BW, Wnent J, Messelken M, Jantzen T, Zeng T, Strickmann B, Bohn A, Fischer H, Scholz J, Fischer M, .
Postresuscitation care with mild therapeutic hypothermia and coronary intervention after out-of-hospital cardiopulmonary resuscitation: a prospective registry analysis.
Crit Care, 15 (2011), R61.  [abstract]

Gruenewald M, Meybohm P, Renner J, Broch O, Caliebe A, Weiler N, Steinfath M, Scholz J, Bein B.
Effect of norepinephrine dosage and calibration frequency on accuracy of pulse contour-derived cardiac output.
Crit Care, 15 (2011), R22.  [abstract]

Wolf A, Caliebe A, Thomas NS, Ball EV, Mort M, Stenson PD, Krawczak M, Cooper DN.
Single base-pair substitutions at the translation initiation sites of human genes as a cause of inherited disease.
Hum Mutat, 32 (2011), 1137–43.  [abstract]

Nebel A, Kleindorp R, Caliebe A, Nothnagel M, Blanché H, Junge O, Wittig M, Ellinghaus D, Flachsbart F, Wichmann HE, Meitinger T, Nikolaus S, Franke A, Krawczak M, Lathrop M, Schreiber S.
A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals.
Mech Ageing Dev, 132 (2011), 324-30.  [abstract]

Jochens A, Caliebe A, Rösler U, Krawczak M.
Empirical evaluation reveals best fit of a logistic mutation model for human Y-chromosomal microsatellites.
Genetics, 189 (2011), 1403-11.  [abstract]

Kapischke M, Schulze H, Caliebe A.
Self-fixating mesh for the Lichtenstein procedure--a prestudy.
Langenbecks Arch Surg, 395 (2010), 317-22.  [abstract]

von Wurmb-Schwark N, Schwark T, Caliebe A, Drenske C, Nikolaus S, Schreiber S, Nebel A.
Low level of the mtDNA(4977) deletion in blood of exceptionally old individuals.
Mech Ageing Dev, 131 (2010), 179-84.  [abstract]

Moritz JD, Hoffmann B, Meuser SH, Sehr DH, Caliebe A, Heller M.
[Is ultrasound equal to X-ray in pediatric fracture diagnosis?].
Rofo, 182 (2010), 706-14.  [abstract]

Caliebe A, Kleindorp R, Blanché H, Christiansen L, Puca AA, Rea IM, Slagboom E, Flachsbart F, Christensen K, Rimbach G, Schreiber S, Nebel A.
No or only population-specific effect of PON1 on human longevity: a comprehensive meta-analysis.
Ageing Res Rev, 9 (2010), 238-44.  [abstract]

Flachsbart F, Caliebe A, Nothnagel M, Kleindorp R, Nikolaus S, Schreiber S, Nebel A.
Depletion of potential A2M risk haplotype for Alzheimer's disease in long-lived individuals.
Eur J Hum Genet, 18 (2010), 59-61.  [abstract]

Caliebe A, Jochens A, Krawczak M, Rösler U.
A Markov chain description of the stepwise mutation model: local and global behaviour of the allele process.
J Theor Biol, 266 (2010), 336-42.  [abstract]

Flachsbart F, Franke A, Kleindorp R, Caliebe A, Blanché H, Schreiber S, Nebel A.
Investigation of genetic susceptibility factors for human longevity - A targeted nonsynonymous SNP study.
Mutat Res, 694 (2010), 13-9.  [abstract]

Wolf A, Millar DS, Caliebe A, Horan M, Newsway V, Kumpf D, Steinmann K, Chee IS, Lee YH, Mutirangura A, Pepe G, Rickards O, Schmidtke J, Schempp W, Chuzhanova N, Kehrer-Sawatzki H, Krawczak M, Cooper DN.
A gene conversion hotspot in the human growth hormone (GH1) gene promoter.
Hum Mutat, 30 (2009), 239-47.  [abstract]

Lu TT, Lao O, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Nielsen F, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Uitterlinden AG, Gieger C, Wichmann HE, Ruether A, Schreiber S, Becker C, Nürnberg P, Nelson MR, Kayser M, Krawczak M.
An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population.
Eur J Hum Genet, 17 (2009), 967-75.  [abstract]

Flachsbart F, Caliebe A, Kleindorp R, Blanché H, von Eller-Eberstein H, Nikolaus S, Schreiber S, Nebel A.
Association of FOXO3A variation with human longevity confirmed in German centenarians.
Proc Natl Acad Sci U S A, 106 (2009), 2700-5.  [abstract]

Nebel A, Flachsbart F, Till A, Caliebe A, Blanché H, Arlt A, Häsler R, Jacobs G, Kleindorp R, Franke A, Shen B, Nikolaus S, Krawczak M, Rosenstiel P, Schreiber S.
A functional EXO1 promoter variant is associated with prolonged life expectancy in centenarians.
Mech Ageing Dev, 130 (2009), 691-99.  [abstract]

Kapischke M, Schulz T, Schipper T, Tensfeldt J, Caliebe A.
Open versus laparoscopic incisional hernia repair: something different from a meta-analysis.
Surg Endosc, 22 (2008), 2251-60.  [abstract]

Lao O, Lu TT, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Uitterlinden AG, Gieger C, Wichmann HE, Rüther A, Schreiber S, Becker C, Nürnberg P, Nelson MR, Krawczak M, Kayser M.
Correlation between genetic and geographic structure in Europe.
Curr Biol, 18 (2008), 1241-8.  [abstract]

Caliebe A.
Mathematische Modelle in der Populationsgenetik.
medgen, 20 (2008), 282-287.  [abstract]

Haenisch S, May K, Wegner D, Caliebe A, Cascorbi I, Siegmund W.
Influence of genetic polymorphisms on intestinal expression and rifampicin-type induction of ABCC2 and on bioavailability of talinolol.
Pharmacogenet Genomics, 18 (2008), 357-65.  [abstract]

Caliebe A, Neininger R, Krawczak M, Rösler U.
On the length distribution of external branches in coalescence trees: genetic diversity within species.
Theor Popul Biol, 72 (2007), 245-52.  [abstract]

Krawczak M, Caliebe A, Croucher PJ, Schmidtke J.
On the testing load incurred by cascade genetic carrier screening for Mendelian disorders: a brief report.
Genet Test, 11 (2007), 417-9.  [abstract]

Caliebe A, Hirschbiegel J.
Philipp der Kühne, Johann Ohnefurcht und der höfische Geschenkverkehr zum neuen Jahr um 1400.
In: Paris, capitale des ducs de Bourgogne, Werner Paravicini, Bertrand Schnerb (Eds.), Thorbecke (Ostfildern), Beihefte der Francia, 64 (2007), 219-63. 

Renders L, Frisman M, Ufer M, Mosyagin I, Haenisch S, Ott U, Caliebe A, Dechant M, Braun F, Kunzendorf U, Cascorbi I.
CYP3A5 genotype markedly influences the pharmacokinetics of tacrolimus and sirolimus in kidney transplant recipients.
Clin Pharmacol Ther, 81 (2007), 228-34.  [abstract]

Caliebe A.
Properties of the maximum a posteriori path estimator in hidden Markov models.
IEEE Trans. Inform. Theory, 52 (2006), 41-51. 

Kapischke M, Caliebe A, Tepel J, Schulz T, Hedderich J.
Open versus laparoscopic appendicectomy: a critical review.
Surg Endosc, 20 (2006), 1060-8.  [abstract]

Steffens M, Lamina C, Illig T, Bettecken T, Vogler R, Entz P, Suk EK, Toliat MR, Klopp N, Caliebe A, König IR, Köhler K, Ludemann J, Diaz Lacava A, Fimmers R, Lichtner P, Ziegler A, Wolf A, Krawczak M, Nūrnberg P, Hampe J, Schreiber S, Meitinger T, Wichmann HE, Roeder K, Wienker TF, Baur MP.
SNP-based analysis of genetic substructure in the German population.
Hum Hered, 62 (2006), 20-9.  [abstract]

Caliebe A, Freitag S, Krawczak M.
Stochastische Modelle für Interaktion und Effektmodifikation.
Medizinische genetik, 17 (2005), 14-9. 

Wolf A, Caliebe A, Junge O, Krawczak M.
Forensic interpretation of Y-chromosomal DNA mixtures.
Forensic Sci Int, 152 (2005), 209-13.  [abstract]

Caliebe A.
Representation of fixed points of a smoothing transformation.
In: Mathematics and Computer Science III, editors: M. Drmota, P. Flajolet, D. Gardy, B. Gittenberger, Trends in Mathematics, Birkhäuser Verlag Basel, (2004), 311-24. 

Caliebe A, Rösler U.
Fixed points with finite variance of a smoothing transformation.
Stochastic Process Appl, 107 (2003), 105-29. 

Caliebe A.
Symmetric fixed points of a smoothing transformation.
Adv in Appl Probab, 35 (2003), 377-94. 

Caliebe A, Rösler U.
Convergence of the maximum a posteriori path estimator in hidden Markow models.
IEEE Transactions on Information Theory, 48 (2002), 1750-1758. 

Riessner T, Woelk F, Abshagen-Keunecke M, Caliebe A, Hansen UP.
A new level detector for ion channel analysis.
J Membr Biol, 189 (2002), 105-18.  [abstract]

Caliebe A, Rösler U, Hansen UP.
A χ² test for model determination and sublevel detection in ion channel analysis.
J Membr Biol, 185 (2002), 25-41.  [abstract]