Prof. Dr. Ruth Schmitz-Streit

Education

1989	Diploma, (Microbiology) University of Marburg, Germany
1992	Ph.D., (Microbiology) University of Marburg, Germany
1994 - 1996	Postdoc, University of California, Berkeley, California, USA
7/2001	Habilitation

Academic Positions

1996 - 2004	University of Göttingen, Department of Microbiology & Genetics
2004 - today	University of Kiel, Department of Microbiology

Selected Publications

2011

• Schmitz, RA, Jäger D, Jellen-Ritter, A, Babski, J, Soppa, J, Marchfelder, A
  Archaea employ small RNA as regulators.
  In Regulatory RNAs in Prokaryotes (Hess, W.R. and Marchfelder, A. eds.), Springer, Vienna. No abstract available.
• Ilmberger N, Meske D, Juergensen J, Schulte M, Barthen P, Rabausch U, Angelov A, Mientus M, Liebl W, Schmitz RA, Streit WR
  Metagenomic cellulases highly tolerant in the presence of ionic liquids - linking thermostability and halotolerance.
  Applied microbiology and biotechnology; 2011 Dec 6. [Epub ahead of print]
• Thomas F, Diaz-Bone R, Würfel O, Huber B, Weidenbach K, Schmitz RA, Hensel R
  Connection between multimetal(loid) methylation in methanoarchaea and central intermediates of methanogenesis.
  Appl. Environ Microbiol. 77, 8669-8675, 2011 Oct 14. [Epub ahead of print]
• Ehlers C, Jäger D, Schmitz, RA
  Establishing a markerless genetic exchange system for Methanosarcina mazei strain Gö1 for constructing chromosomal mutants of small RNA genes
  Archaea 2011:439608. Epub 2011 Sep 20
• Egert M, Schmidt I, Höhne H-M, Lachnit T, Schmitz RA, Breves R
  Ribosomal RNA-based profiling of bacteria in the axilla of healthy males suggests right-left asymmetry in bacterial activity
  FEMS Microbiology Ecology 77: 146-53.
• Lachnit T, Meske D, Wahl M, Harder T, Schmitz RA.
  Epibacterial community patterns on marine macroalgae are host-specific but temporally variable
  Environmental Microbiology13(3): 655-65.
• Milenkov M, Thummer R, Glöer J, Grötzinger J, Jung S, Schmitz RA
  Insights into membrane association of Klebsiella pneumoniae NifL under N₂ - fixing conditions by mutational analysis
  J Bacteriology 193(3): 695-705.

2010

• Barz M, Beimgraben C, Staller T, Germer F, Opitz F, Marquardt C, Schwarz C, Gutekunst C, Vanselow KH, Schmitz RA, LaRoche J, Schulz R, Appel J.
  Distribution analysis of hydrogenases in surface waters of marine and freshwater environments
  PLos ONE 5(11): e13846
• Weidenbach K, Ehlers C, Kock J, Schmitz RA.
  NrpRII mediates contacts between NrpRI and general transcription factors in the archaeon Methanosarcina mazei Gö1
  FEBS J. 277: 4398-4411
• Weiland N, Löscher C, Metzger R, Schmitz RA.
  Construction and screening marine metagenomic libraries.
  Methods Mol Biol. 668: 51-65

2009

• Jäger D, Sharma CM, Thomsen J, Ehlers C, Vogel J, Schmitz RA.
  Deep sequencing analysis of the Methanosarcina mazei Gö1 transcriptome in response to nitrogen availability
  Proc Natl Acad Sci U S A.106(51): 21878-82
• Schmeisser C, Liesegang H, Krysciak D, Bakkou N, Le Quéré A, Wollherr A, Heinemeyer I, Morgenstern B, Pommerening-Röser A, Flores M, Palacios R, Brenner S, Gottschalk G, Schmitz RA, Broughton WJ, Perret X, Strittmatter AW, Streit WR.
  Rhizobium sp. NGR234 possesses a remarkable number of secretion systems
  Appl Environ Microbiol. 75(12): 4035-45

2008

• Glöer J, Thummer R, Ullrich H, Schmitz RA.
  Towards understanding the nitrogen signal transduction for nif gene expression in Klebsiella pneumoniae
  FEBS J. 275(24): 6281-94
• Weidenbach K, Ehlers C, Kock J, Ehrenreich A, Schmitz RA.
  Insights into the NrpR regulon in Methanosarcina mazei Gö1
  Archives of Microbiology 190(3): 319-32
• Weidenbach K, Glöer J, Ehlers C, Sandman K, Reeve JN, Schmitz RA.
  Deletion of the archaeal histone in Methanosarcina mazei Gö1 results in reduced growth and genomic transcription.
  Mol Microbiol. 67(3): 662-71

2007

• Urban JH, Papenfort K, Thomsen J, Schmitz RA, Vogel J.
  A Conserved Small RNA Promotes Discoordinate Expression of the glmUS Operon mRNA to Activate GlmS Synthesis.
  J Mol Biol., 373(3): 521-8
• Thummer R, Klimmek O, Schmitz RA.
  Biochemical Studies of Klebsiella pneumoniae NifL Reduction Using Reconstituted Partial Anaerobic Respiratory Chains of Wolinella succinogenes.
  J Biol Chem., 282(17): 12517-12526

2006

• Veit K, Ehlers C, Ehrenreich A, Salmon K, Hovey R, Gunsalus RP, Deppenmeier U, Schmitz RA
  Global transcriptional analysis of Methanosarcina mazei strain Gö1 under different nitrogen availabilities.
  Molecular Genetics and Genomics, 276(1): 41-55

2005

• Reeve JN, Schmitz RA
  Biology, biochemistry and the molecular machinery of Archaea.
  Curr Opin Microbiol. 8(6): 627-9.
• Veit K, Ehlers C, Schmitz RA
  Effects of nitrogen and carbon sources on transcription of soluble methyltransferases in Methanosarcina mazei strain Gö1.
  J. Bacteriology 187, 6147-6154.
• Ehlers C, Weidenbach K, Veit K, Deppenmeier U, Metcalf W, Schmitz RA
  Development of genetic methods and construction of chromosomal glnK₁ mutant in Methanosarcina mazei strain Gö1.
  Molecular Genetics and Genomics 273, 290-298.
• Ehlers C, Weidenbach K, Veit K, Forchhammer K, Schmitz RA
  Unique mechanistic features of post translational regulation of glutamin synthetase activity in Methanosarcina mazei in response to nitrogen availability.
  Molecular Microbiology 55, 1841-1854.

2004

• Streit WR, Schmitz RA
  Metagenomics - the key to the uncultured microbes.
  Current Opinion in Microbiology 7, 492 - 498.
• Stips J, Thummer R, Neumann M, Schmitz RA
  GlnK effects complex formation between NifA and NifL in Klebsiella pneumoniae.
  European Journal of Biochemistry. 271, 3379-3388.
• Schmitz RA, Achebach S, Unden G
  Analysis of Fumarate nitrate reductase regulator as oxygen sensor in Escherichia coli. In 'Methods in Enzymology, Volume 381, Oxygen sensing'.
  Sen CK & Semenza GL (eds.), Academic press Inc., New York. pp 628. No abstract available.
• Streit WR, Schmitz RA, Perret X, Staehelin C, Deakin WJ, Raasch C, Liesegang H, Broughton WJ
  An Evolutionary Hot Spot: the pNGR234b Replicon of Rhizobium sp. Strain NGR234.
  J. Bacteriology 186, 535 - 542.

2003

• Schmeisser C, Stöckigt C, Raasch C, Wingender J, Timmis KN, Wenderoth DF, Flemming H-C, Liesegang H, Schmitz RA, Jaeger K-E, Streit WR
  Metagenome Survey of Biofilms in Drinking Water Networks.
  Appl. Environ. Microbiol. 69, 7298-7309.
• Grabbe R, Schmitz RA.
  Oxygen control of nif gene expression in Klebsiella pneumoniae depends on NifL reduction at the cytoplasmic membrane by electrons derived from the reduced quinone pool.
  Eur J Biochem. 270(7): 1555-66.

2002

• Deppenmeier U, Schmitz RA, Gunsalus RP, Fritz HJ, Gottschalk G.
  The genome of Methanosarcina mazei: evidence for lateral gene transfer between bacteria and archaea.
  J Mol Microbiol Biotechnol 4(4): 453-61
• Schmitz RA, Klopprogge K, Grabbe R, Stips J
  Regulation of nitrogen fixation in Klebsiella pneumoniae and Azotobacter vinelandii: NifL, transducing two environmental signals to the nif transcriptional activator NifA .
  In 'Regulatory networks in Prokaryotes' Dürre P & Friedrich B (eds.), p. 65-72, Horizon Scientific press, Norfolk. No abstract available.
• Schmitz RA, Klopprogge K, Grabbe R
  Regulation of nitrogen fixation in Klebsiella pneumoniae and Azotobacter vinelandii: NifL, transducing two environmental signals to the nif transcriptional activator NifA (Minireview). J. Mol. Microbiol. Biotechnol. 4, 235-242.
• Klopprogge K, Grabbe R, Hoppert M, Schmitz RA
  Membrane association of Klebsiella pneumoniae NifL is affected by molecular oxygen and combined nitrogen. Archives of Microbiology, 117, 223-234.
• Klopprogge K, Stips J, Schmitz RA
  The inhibitory form of NifL from Klebsiella  pneumoniae exhibits ATPase activity only when synthesized under nitrogen sufficiency. Biochem. Biophys. Acta 1594, 243-54.
• Ehlers C, Grabbe R, Veit K, Schmitz RA
  Characterization of GlnK1 from Methanosarcina mazei strain Gö1: Complementation of an Escherichia coli glnK mutant strain by M. mazei GlnK1.
  J. Bacteriol. 184: 1028-1040.

2001

• Grabbe R, Kuhn A, Schmitz RA
  Cloning, sequencing and characterization of Fnr from Klebsiella pneumoniae.
  Antonie Van Leeuwenhoek. 79(3-4): 319-26.
• Grabbe R, Klopprogge K, Schmitz RA.
  Fnr Is required for NifL-dependent oxygen control of nif gene expression in Klebsiella pneumoniae.
  J Bacteriol. 183(4): 1385-93.

2000

• Henne A, Schmitz RA, Bömeke M, Gottschalk G, Daniel R
  Screening of environmental DNA libraries for the presence of genes conferring lipolytic activity on Escherichia coli. Appl. Environ. Microbiol. 66: 3113-3116.

1999

• Henne A, Daniel R, Schmitz RA, Gottschalk, G
  Construction of environmental DNA libraries in Escherichia coli and screening for the presence of genes conferring utilization of 4-hydroxybutyrate. Appl. Environ. Microbiol. 65, 3901-3907.

Articles in German

Daniel R, Schmitz RA, Streit W (2002) aus Wattenmeer und Wüstensand. Georgia Augusta. 1: 111-115

additional Publications in PubMed