Our lab has developed two tools: 1) WormExp, a web-based application for gene set enrichment analysis for Caenorhabditis elegans. WormExp is expected to yield novel functional insights into newly determined gene sets. The approach is based on the complete collection of curated high-throughput gene expression data sets for the model nematode Caenorhabditis elegans; 2) ABSSeq, a R package for differential expression analysis of RNA-Seq data, which provides a new normalization approach (namely qtotal), accurate fold change moderation and differential expression inference via absolute counts difference or fold change. See below for details.